Unconventional Imaging Methods in Psoriatic Arthritis.

IF 5.7 2区 医学 Q1 RHEUMATOLOGY
Ioanna Minopoulou, Filippo Fagni, Armin Atzinger, Fredrik Albach, Georg Schett, Gerhard Krönke, Arnd Kleyer, David Simon
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引用次数: 0

Abstract

Purpose of review: Psoriatic arthritis (PsA) is a complex heterogeneous inflammatory disease that affects about one-third of patients with psoriasis. PsA leads to significant physical impairment and reduced quality of life. Therefore, early diagnosis and intervention are critical for improving long-term outcomes. The purpose of this review is to highlight the advantages of unconventional imaging methods in the diagnosis and management of PsA and to discuss recent advancements in imaging technology.

Recent findings: Conventional imaging methods, such as radiography, musculoskeletal ultrasound, and magnetic resonance imaging, have been instrumental in detecting structural joint damage and inflammation. However, these imaging modalities have several limitations, resulting in their inability to detect early disease changes. Recent advancements in imaging technology have led to the development of novel imaging modalities capable of characterizing not only early structural but also molecular aspects of disease activity. These cutting-edge approaches have been lately applied to both psoriasis and PsA patients, offering new insights into disease progression, the transition from psoriasis to PsA, and treatment responses. By providing more detailed and individualized assessments, unconventional imaging modalities may bring us closer to realizing the potential of personalized medicine in the management of PsA.

银屑病关节炎的非常规成像方法。
综述目的:银屑病关节炎(Psoriatic arthritis, PsA)是一种复杂的异质性炎症性疾病,约占银屑病患者的三分之一。PsA会导致严重的身体损伤和生活质量下降。因此,早期诊断和干预对于改善长期预后至关重要。本综述的目的是强调非常规成像方法在PsA诊断和治疗中的优势,并讨论成像技术的最新进展。最近的发现:传统的成像方法,如x线摄影、肌肉骨骼超声和磁共振成像,已经在检测结构性关节损伤和炎症方面发挥了重要作用。然而,这些成像方式有一些局限性,导致它们无法发现早期疾病的变化。最近成像技术的进步导致了新的成像模式的发展,不仅能够表征疾病活动的早期结构方面,而且还能表征疾病活动的分子方面。这些前沿的方法最近被应用于牛皮癣和PsA患者,为疾病进展、牛皮癣到PsA的转变和治疗反应提供了新的见解。通过提供更详细和个性化的评估,非常规成像模式可能使我们更接近实现个性化医疗在PsA管理中的潜力。
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来源期刊
CiteScore
11.20
自引率
0.00%
发文量
41
期刊介绍: This journal aims to review the most important, recently published research in the field of rheumatology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of rheumatologic conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as the many forms of arthritis, osteoporosis and metabolic bone disease, and systemic lupus erythematosus. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.
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