Crystal structure and Hirshfeld surface analysis of N-(4-nitro-phen-yl)-2-(piperidin-1-yl)acetamide (lidocaine analogue).

IF 0.5 Q4 CRYSTALLOGRAPHY
Imane Maimoune, Benson M Kariuki, Abderrazzak El Moutaouakil Ala Allah, Intissar Nchioua, Abdulsalam Alsubari, Joel T Mague, Abdelkader Zarrouk, Youssef Ramli
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引用次数: 0

Abstract

In the title mol-ecule, C13H17N3O3, the substituents on the phenyl ring are rotated slightly out of the mean plane of the ring but the piperidine moiety is nearly perpendicular to that plane. In the crystal, C-H⋯O hydrogen bonds form chains of mol-ecules extending along the c-axis direction, which are linked by C=O⋯π(ring) inter-actions. A Hirshfeld surface analysis showed the majority of inter-molecular inter-actions to be H⋯H contacts while O⋯H/H⋯O contacts are the second most numerous.

N-(4-硝基-苯基)-2-(哌啶-1-基)乙酰胺(利多卡因类似物)的晶体结构和Hirshfeld表面分析。
在标题分子C13H17N3O3中,苯基环上的取代基略微旋转出环的平均平面,但哌啶部分几乎垂直于环的平均平面。在晶体中,C- h⋯O氢键形成沿C轴方向延伸的分子链,这些分子链由C=O⋯π(环)相互作用连接。Hirshfeld表面分析显示,大多数分子间相互作用是H⋯H接触,而O⋯H/H⋯O接触是第二多的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.90
自引率
0.00%
发文量
351
审稿时长
3 weeks
期刊介绍: Acta Crystallographica Section E: Crystallographic Communications is the IUCr''s open-access structural communications journal. It provides a fast, simple and easily accessible publication mechanism for crystal structure determinations of inorganic, metal-organic and organic compounds. The electronic submission, validation, refereeing and publication facilities of the journal ensure rapid and high-quality publication of fully validated structures. The primary article category is Research Communications; these are peer-reviewed articles describing one or more structure determinations with appropriate discussion of the science.
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