Complementary and Alternative Medicine Use in the Last Year of Life: The COMPASS Cancer Cohort Study.

IF 3.2 2区医学 Q2 CLINICAL NEUROLOGY

Journal of pain and symptom management Pub Date : 2025-01-02 DOI:10.1016/j.jpainsymman.2024.12.022

Irene Teo, Michelle Chow, Isha Chaudhry, Chetna Malhotra, Semra Ozdemir, Eric A Finkelstein

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引用次数: 0

Abstract

Context: There has been growing interest in the role of complementary and alternative medicine (CAM) as part of end-of-life care.

Objectives: This study prospectively examined the prevalence, predictors and outcomes of ingestible CAM use among cancer patients in their last year of life in Singapore.

Methods: This study (N = 427) utilized data across 12 months (four time points) prior to patient death. Utilizing mixed effects logistic regressions, we examined sociodemographic, clinical (symptom burden) and treatment-related factors associated with CAM use. Subsequently, the association between patient quality of life (i.e., physical, social, emotional, functional well-being) and CAM use were examined.

Results: Half of the patients (50%) reported using CAM at least once in the last year of life while 36% of patients reported using CAM in the last 3 months of life. Among CAM users, 67% reported using western herbal supplements while 56% reported using traditional Chinese medicine. Further, 27-28% of patients used CAM consistently (i.e., for six months or more). Most patients (73%) reported using CAM as a complementary treatment. Patients who were ethnically Chinese (OR: 5.59, 95% CI: 2.29-13.69), reported less financial difficulties (OR: 0.82, 95% CI: 0.69-0.98), and believed in other curative treatments for cancer (OR: 2.39, 95% CI: 1.00-5.70) were more likely to use CAM. Controlling for time, CAM use (β: 0.60, CI: 0.01-1.19) was associated with higher social well-being.

Conclusions: A significant proportion of terminal cancer patients reported using CAM as a complementary treatment in the last year of life.

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生命最后一年补充和替代药物的使用：COMPASS癌症队列研究。

背景：作为临终关怀的一部分，人们对补充和替代医学（CAM）的作用越来越感兴趣。目的：本研究前瞻性地调查了新加坡癌症患者在生命最后一年使用可摄取CAM的患病率、预测因素和结果。方法：本研究（N=427）利用患者死亡前12个月（4个时间点）的数据。利用混合效应逻辑回归，我们检查了与辅助治疗使用相关的社会人口统计学、临床（症状负担）和治疗相关因素。随后，研究了患者生活质量（即身体、社会、情感、功能健康）与CAM使用之间的关系。结果：一半的患者（50%）报告在生命的最后一年至少使用过一次CAM， 36%的患者在生命的最后3个月报告使用过CAM。在CAM使用者中，67%的人使用西方草药补充剂，56%的人使用传统中药。此外，27-28%的患者持续使用CAM（即6个月或更长时间）。大多数患者（73%）报告使用CAM作为补充治疗。华裔患者（OR: 5.59, 95% CI: 2.29 -13.69），经济困难较少（OR: 0.82, 95% CI: 0.69 - 0.98），并相信其他癌症治疗方法（OR: 2.39, 95% CI: 1.00 - 5.70）更有可能使用CAM。控制时间，CAM的使用（β: 0.60, CI: 0.01 - 1.19）与较高的社会幸福感相关。结论：在生命的最后一年，有相当比例的晚期癌症患者报告使用CAM作为补充治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of pain and symptom management 医学-临床神经学

CiteScore

8.90

自引率

6.40%

发文量

821

审稿时长

26 days

期刊介绍： The Journal of Pain and Symptom Management is an internationally respected, peer-reviewed journal and serves an interdisciplinary audience of professionals by providing a forum for the publication of the latest clinical research and best practices related to the relief of illness burden among patients afflicted with serious or life-threatening illness.