Effectiveness of nurse-led care in patients with rheumatoid arthritis: a systematic review and meta-analysis.

IF 1.3 Q4 HEALTH CARE SCIENCES & SERVICES
Lin Yang, Peng Xiang, Guifang Pi, Ting Wen, Li Liu, Dan Liu
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Abstract

Objectives: This study sought to assess the effectiveness of nurse-led care (NLC) in patients with rheumatoid arthritis (RA).

Methods: We conducted a comprehensive search of the Cochrane Library, Web of Science, PubMed, Embase, CINAHL, ClinicalTrials.gov databases and the references from relevant literature published prior to May 2023. Two independent reviewers assessed the studies using population/intervention/comparison/outcome/study criteria, and quantitative tools were used to gauge the methodological quality of the included studies. Independent quality assessments were carried out using the Cochrane Collaboration's risk-of-bias tool. Effect sizes were determined using mean difference (MD) or standardised mean difference (SMD) with corresponding 95% CIs.

Results: Ultimately, 14 articles were included, encompassing a total of 3369 RA patients. NLC exhibited significant advantages in the primary outcome, disease activity (MD =-0.09, 95% CI (-0.17 to -0.01)), and the secondary outcome, self-efficacy (MD=0.40, 95% CI (0.03, 0.77)). In subgroup analysis, NLC was more effective in reducing disease activity compared with usual care (MD=-0.15, 95% CI (-0.26 to -0.04)), and there was no significant difference in disease activity reduction between NLC and rheumatologist-led care (MD=-0.02, 95% CI (-0.14, 0.10)). In terms of self-efficacy, no significant difference was observed between NLC and usual care (SMD=0.56, 95% CI (-0.09, 1.21)) or between NLC and rheumatologist-led care (SMD=0.20, 95% CI (-0.19, 0.59). When comparing other secondary outcomes (pain, satisfaction, quality of life, fatigue, stiffness, physical function and psychological status), the effectiveness of NLC for RA patients was similar to that of the control group, with no statistically significant differences.

Conclusions: NLC proves highly effective in managing RA patients, surpassing usual care and equating to rheumatologist-led care in primary and some secondary outcomes. It may be feasible to allow nurses to participate in the disease management of some RA patients instead of doctors.

Prospero registration number: CRD42022362071.

类风湿性关节炎患者护士主导护理的有效性:系统回顾和荟萃分析。
目的:本研究旨在评估护士主导护理(NLC)在类风湿关节炎(RA)患者中的有效性。方法:全面检索Cochrane Library、Web of Science、PubMed、Embase、CINAHL、ClinicalTrials.gov数据库,并检索2023年5月前发表的相关文献。两名独立审稿人使用人群/干预/比较/结果/研究标准对研究进行评估,并使用定量工具衡量纳入研究的方法学质量。使用Cochrane Collaboration的风险偏倚工具进行独立的质量评估。效应量采用平均差(MD)或标准化平均差(SMD)确定,相应的ci为95%。结果:最终纳入14篇文章,共3369例RA患者。NLC在主要结局——疾病活动性(MD= -0.09, 95% CI(-0.17至-0.01))和次要结局——自我效能(MD=0.40, 95% CI(0.03, 0.77))中表现出显著优势。在亚组分析中,与常规护理相比,NLC在降低疾病活动性方面更有效(MD=-0.15, 95% CI(-0.26至-0.04)),NLC与风湿病学家主导的护理在降低疾病活动性方面无显著差异(MD=-0.02, 95% CI(-0.14, 0.10))。在自我效能方面,NLC与常规护理(SMD=0.56, 95% CI(-0.09, 1.21))或NLC与风湿病学家主导的护理(SMD=0.20, 95% CI(-0.19, 0.59))之间无显著差异。在比较其他次要结局(疼痛、满意度、生活质量、疲劳、僵硬、身体功能和心理状态)时,NLC治疗RA患者的有效性与对照组相似,差异无统计学意义。结论:NLC在治疗类风湿性关节炎患者方面被证明是非常有效的,在主要和一些次要结果方面超过了常规护理,等同于风湿病学家主导的护理。允许护士代替医生参与部分RA患者的疾病管理可能是可行的。普洛斯彼罗注册号:CRD42022362071。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMJ Open Quality
BMJ Open Quality Nursing-Leadership and Management
CiteScore
2.20
自引率
0.00%
发文量
226
审稿时长
20 weeks
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