Human intention recognition for trauma resuscitation: An interpretable deep learning approach for medical process data

IF 4 2区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Keyi Li , Mary S. Kim , Wenjin Zhang , Sen Yang , Genevieve J. Sippel , Aleksandra Sarcevic , Randall S. Burd , Ivan Marsic
{"title":"Human intention recognition for trauma resuscitation: An interpretable deep learning approach for medical process data","authors":"Keyi Li ,&nbsp;Mary S. Kim ,&nbsp;Wenjin Zhang ,&nbsp;Sen Yang ,&nbsp;Genevieve J. Sippel ,&nbsp;Aleksandra Sarcevic ,&nbsp;Randall S. Burd ,&nbsp;Ivan Marsic","doi":"10.1016/j.jbi.2024.104767","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Trauma resuscitation is the initial evaluation and management of injured patients in the emergency department. This time-critical process requires the simultaneous pursuit of multiple resuscitation goals. Recognizing whether the required goal is being pursued can reduce errors in goal-related task performance and improve patient outcomes. The intention to pursue a goal can often be inferred from ongoing and completed treatment activities, but monitoring goal pursuit is cognitively demanding and prone to errors. We introduced an interpretable deep learning-based approach to aid decision making by automatically recognizing goal pursuit during trauma resuscitation.</div></div><div><h3>Methods</h3><div>We developed a predictive model to recognize the pursuit of two resuscitation goals: airway stabilization and circulatory support. We used event logs of 381 pediatric trauma resuscitations from August 2014 to November 2022 to train a neural network model with a dual-GRU structure that learns from both time-level and activity-type-level features. Our model makes predictions based on a sequence of activities and corresponding timestamps. To enhance the model and facilitate interpretation of predictions, we used the attention weights assigned by our model to represent the importance of features. These weights identified the critical time points and contributing activities during a goal pursuit.</div></div><div><h3>Results</h3><div>Our model achieved an average area under the receiver operating characteristic curve (AUC) score of 0.84 for recognizing airway stabilization and 0.83 for recognizing circulatory support. The most contributing activities and timestamps were aligned with domain knowledge.</div></div><div><h3>Conclusion</h3><div>Our interpretable predictive model can recognize provider intention based on a limited number of treatment activities. The model outperformed existing predictive models for medical events in accuracy and in interpretability. Integrating our model into a decision-support system would automate the tracking of provider actions, optimizing workflow to ensure timely delivery of care.</div></div>","PeriodicalId":15263,"journal":{"name":"Journal of Biomedical Informatics","volume":"161 ","pages":"Article 104767"},"PeriodicalIF":4.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomedical Informatics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1532046424001850","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0

Abstract

Objective

Trauma resuscitation is the initial evaluation and management of injured patients in the emergency department. This time-critical process requires the simultaneous pursuit of multiple resuscitation goals. Recognizing whether the required goal is being pursued can reduce errors in goal-related task performance and improve patient outcomes. The intention to pursue a goal can often be inferred from ongoing and completed treatment activities, but monitoring goal pursuit is cognitively demanding and prone to errors. We introduced an interpretable deep learning-based approach to aid decision making by automatically recognizing goal pursuit during trauma resuscitation.

Methods

We developed a predictive model to recognize the pursuit of two resuscitation goals: airway stabilization and circulatory support. We used event logs of 381 pediatric trauma resuscitations from August 2014 to November 2022 to train a neural network model with a dual-GRU structure that learns from both time-level and activity-type-level features. Our model makes predictions based on a sequence of activities and corresponding timestamps. To enhance the model and facilitate interpretation of predictions, we used the attention weights assigned by our model to represent the importance of features. These weights identified the critical time points and contributing activities during a goal pursuit.

Results

Our model achieved an average area under the receiver operating characteristic curve (AUC) score of 0.84 for recognizing airway stabilization and 0.83 for recognizing circulatory support. The most contributing activities and timestamps were aligned with domain knowledge.

Conclusion

Our interpretable predictive model can recognize provider intention based on a limited number of treatment activities. The model outperformed existing predictive models for medical events in accuracy and in interpretability. Integrating our model into a decision-support system would automate the tracking of provider actions, optimizing workflow to ensure timely delivery of care.

Abstract Image

创伤复苏的人类意图识别:医疗过程数据的可解释深度学习方法。
目的:创伤复苏是急诊科对受伤患者的初步评估和处理。这个时间紧迫的过程需要同时追求多个复苏目标。认识到是否正在追求所需的目标可以减少与目标相关的任务执行中的错误,并改善患者的治疗效果。追求目标的意图通常可以从正在进行和完成的治疗活动中推断出来,但监测目标追求是认知上的要求,容易出错。我们引入了一种可解释的基于深度学习的方法,通过自动识别创伤复苏过程中的目标追求来辅助决策。方法:我们开发了一个预测模型来识别两个复苏目标:气道稳定和循环支持。我们使用2014年8月至2022年11月381例儿童创伤复苏的事件日志来训练具有双gru结构的神经网络模型,该模型同时学习时间水平和活动类型水平的特征。我们的模型根据一系列活动和相应的时间戳进行预测。为了增强模型并促进预测的解释,我们使用模型分配的注意力权重来表示特征的重要性。这些权重确定了目标追求过程中的关键时间点和贡献活动。结果:我们的模型在识别气道稳定和识别循环支持方面的接受者工作特征曲线下的平均面积(AUC)得分分别为0.84和0.83。贡献最大的活动和时间戳与领域知识保持一致。结论:我们的可解释预测模型可以根据有限的治疗活动识别提供者的意图。该模型在准确性和可解释性方面优于现有的医疗事件预测模型。将我们的模型集成到决策支持系统中,可以自动跟踪提供者的行动,优化工作流程,确保及时提供护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Biomedical Informatics
Journal of Biomedical Informatics 医学-计算机:跨学科应用
CiteScore
8.90
自引率
6.70%
发文量
243
审稿时长
32 days
期刊介绍: The Journal of Biomedical Informatics reflects a commitment to high-quality original research papers, reviews, and commentaries in the area of biomedical informatics methodology. Although we publish articles motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, and translational bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices; evaluations of implemented systems (including clinical trials of information technologies); or papers that provide insight into a biological process, a specific disease, or treatment options would generally be more suitable for publication in other venues. Papers on applications of signal processing and image analysis are often more suitable for biomedical engineering journals or other informatics journals, although we do publish papers that emphasize the information management and knowledge representation/modeling issues that arise in the storage and use of biological signals and images. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report and an effort is made to address the generalizability and/or range of application of that methodology. Note also that, given the international nature of JBI, papers that deal with specific languages other than English, or with country-specific health systems or approaches, are acceptable for JBI only if they offer generalizable lessons that are relevant to the broad JBI readership, regardless of their country, language, culture, or health system.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信