Robotic arm-assisted medial compartment knee arthroplasty is a cost-effective intervention at ten-year follow-up.

IF 4.9 1区 医学 Q1 ORTHOPEDICS
Mark J G Blyth, Nick D Clement, Xin Y Choo, James Doonan, Angus MacLean, Bryn G Jones
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引用次数: 0

Abstract

Aims: The aim of this study was to perform an incremental cost-utility analysis and assess the impact of differential costs and case volume on the cost-effectiveness of robotic arm-assisted medial unicompartmental knee arthroplasty (rUKA) compared to manual (mUKA).

Methods: Ten-year follow-up of patients who were randomized to rUKA (n = 64) or mUKA (n = 65) was performed. Patients completed the EuroQol five-dimension health questionnaire preoperatively, at three months, and one, two, five, and ten years postoperatively, which was used to calculate quality-adjusted life years (QALY) gained and the incremental cost-effectiveness ratio (ICER). Costs for the index and additional surgery and healthcare costs were calculated.

Results: mUKA had a lower survival for reintervention (84.8% (95% CI 76.2 to 93.4); p = 0.001), all-cause revision (88.9% (95% CI 81.3 to 96.5); p = 0.007) and aseptic revision (91.9% (95% CI 85.1 to 98.7); p = 0.023) when compared to the rUKA group at ten years, which was 100%. The rUKA group had a greater QALY gain per patient (mean difference 0.186; p = 0.651). Overall rUKA was the dominant intervention, being cost-saving and more effective with a greater health-related quality of life gain. On removal of infected reinterventions (n = 2), the ICER was £757 (not discounted) and £481 (discounted). When including all reintervention costs, rUKA was cost-saving when more than 100 robotic cases were performed per year. When removing the infected cases, rUKA was cost-saving when undertaking more than 800 robotic cases per year.

Conclusion: rUKA had lower reintervention and revision risks at ten years, which was cost-saving and associated with a greater QALY gain, and was the dominant procedure. When removing the cost of infection, which could be a random event, rUKA was a cost-effective intervention with an ICER (£757) which was lower than the willingness-to-pay threshold (£20,000).

机械臂辅助内侧隔室膝关节置换术是一种具有成本效益的干预措施。
目的:本研究的目的是进行增量成本-效用分析,并评估与人工(mUKA)相比,机械臂辅助内侧单室膝关节置换术(rUKA)的差异成本和病例量对成本效益的影响。方法:对随机选择rUKA组(64例)和mUKA组(65例)的患者进行10年随访。患者术前、术后3个月、1年、2年、5年、10年分别填写EuroQol五维健康问卷,用于计算获得的质量调整生命年(QALY)和增量成本-效果比(ICER)。计算了该指数的成本以及额外的手术和医疗费用。结果:mUKA的再干预生存率较低(84.8% (95% CI 76.2 ~ 93.4);p = 0.001),全因修正(88.9%,95% CI 81.3 ~ 96.5);p = 0.007)和无菌修订(91.9% (95% CI 85.1 ~ 98.7);p = 0.023),与十年后的rUKA组相比,成功率为100%。rUKA组每位患者的QALY增加更大(平均差0.186;P = 0.651)。总的来说,rUKA是主要的干预措施,节省了成本,更有效,健康相关的生活质量也得到了提高。在移除受感染的再干预物(n = 2)时,ICER为757英镑(未打折)和481英镑(打折)。当包括所有再干预费用时,rUKA每年进行100多例机器人手术,节省了成本。在移除感染病例时,rUKA每年使用800多台机器人进行手术,节省了成本。结论:rUKA术后10年再干预和翻修风险较低,节省成本,QALY获益较大,是优势手术。在排除感染成本(这可能是一个随机事件)后,rUKA是一种具有成本效益的干预措施,其ICER(757英镑)低于支付意愿阈值(2万英镑)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bone & Joint Journal
Bone & Joint Journal ORTHOPEDICS-SURGERY
CiteScore
9.40
自引率
10.90%
发文量
318
期刊介绍: We welcome original articles from any part of the world. The papers are assessed by members of the Editorial Board and our international panel of expert reviewers, then either accepted for publication or rejected by the Editor. We receive over 2000 submissions each year and accept about 250 for publication, many after revisions recommended by the reviewers, editors or statistical advisers. A decision usually takes between six and eight weeks. Each paper is assessed by two reviewers with a special interest in the subject covered by the paper, and also by members of the editorial team. Controversial papers will be discussed at a full meeting of the Editorial Board. Publication is between four and six months after acceptance.
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