Using artificial intelligence and statistics for managing peritoneal metastases from gastrointestinal cancers.

IF 2.5 3区 生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Adam Wojtulewski, Aleksandra Sikora, Sean Dineen, Mustafa Raoof, Aleksandra Karolak
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引用次数: 0

Abstract

Objective: The primary objective of this study is to investigate various applications of artificial intelligence (AI) and statistical methodologies for analyzing and managing peritoneal metastases (PM) caused by gastrointestinal cancers.

Methods: Relevant keywords and search criteria were comprehensively researched on PubMed and Google Scholar to identify articles and reviews related to the topic. The AI approaches considered were conventional machine learning (ML) and deep learning (DL) models, and the relevant statistical approaches included biostatistics and logistic models.

Results: The systematic literature review yielded nearly 30 articles meeting the predefined criteria. Analyses of these studies showed that AI methodologies consistently outperformed traditional statistical approaches. In the AI approaches, DL consistently produced the most precise results, while classical ML demonstrated varied performance but maintained high predictive accuracy. The sample size was the recurring factor that increased the accuracy of the predictions for models of the same type.

Conclusions: AI and statistical approaches can detect PM developing among patients with gastrointestinal cancers. Therefore, if clinicians integrated these approaches into diagnostics and prognostics, they could better analyze and manage PM, enhancing clinical decision-making and patients' outcomes. Collaboration across multiple institutions would also help in standardizing methods for data collection and allowing consistent results.

使用人工智能和统计学来管理胃肠道癌症的腹膜转移。
目的:本研究的主要目的是探讨人工智能(AI)和统计方法在胃肠道癌症引起的腹膜转移(PM)分析和管理中的各种应用。方法:在PubMed和谷歌Scholar上综合研究相关关键词和检索标准,识别与该主题相关的文章和综述。考虑的人工智能方法是传统的机器学习(ML)和深度学习(DL)模型,相关的统计方法包括生物统计学和逻辑模型。结果:系统文献综述得到符合预定标准的近30篇文章。对这些研究的分析表明,人工智能方法始终优于传统的统计方法。在人工智能方法中,深度学习始终产生最精确的结果,而经典ML表现出不同的性能,但保持了很高的预测准确性。样本量是增加同类型模型预测准确性的反复出现的因素。结论:人工智能和统计学方法可以检测胃肠道肿瘤患者发生的PM。因此,如果临床医生将这些方法整合到诊断和预后中,他们可以更好地分析和管理PM,提高临床决策和患者预后。多个机构之间的合作也将有助于数据收集方法的标准化,并允许一致的结果。
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来源期刊
Briefings in Functional Genomics
Briefings in Functional Genomics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-GENETICS & HEREDITY
CiteScore
6.30
自引率
2.50%
发文量
37
审稿时长
6-12 weeks
期刊介绍: Briefings in Functional Genomics publishes high quality peer reviewed articles that focus on the use, development or exploitation of genomic approaches, and their application to all areas of biological research. As well as exploring thematic areas where these techniques and protocols are being used, articles review the impact that these approaches have had, or are likely to have, on their field. Subjects covered by the Journal include but are not restricted to: the identification and functional characterisation of coding and non-coding features in genomes, microarray technologies, gene expression profiling, next generation sequencing, pharmacogenomics, phenomics, SNP technologies, transgenic systems, mutation screens and genotyping. Articles range in scope and depth from the introductory level to specific details of protocols and analyses, encompassing bacterial, fungal, plant, animal and human data. The editorial board welcome the submission of review articles for publication. Essential criteria for the publication of papers is that they do not contain primary data, and that they are high quality, clearly written review articles which provide a balanced, highly informative and up to date perspective to researchers in the field of functional genomics.
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