Two-Dimensional Shear Wave Ultrasound Elastography for Monitoring Pediatric Liver Transplantation: A Review of Recent Advances.

IF 1.4 4区 医学 Q3 PEDIATRICS
Mohamed Abdulla, Maryam Abdulla, Hakima Al-Hashimi, Hasan M Isa, Kevin Dunne, James Blackwell
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引用次数: 0

Abstract

Pediatric liver transplantation (PLT) is a life-saving procedure for children with end-stage liver disease. However, post-transplant monitoring, particularly the diagnosis and prognosis of complications such as allograft fibrosis, remains challenging. Traditionally, liver biopsy has been the gold standard for assessing allograft fibrosis, despite its invasive nature and inherent procedural risks. Recently, shear wave ultrasound elastography (SWE) has seen increasing use as a noninvasive method to provide real-time, quantitative measurements of liver stiffness as a proxy for fibrosis. In this review, the latest developments in the use of SWE as a method to assess allograft fibrosis post-PLT are presented, including the current technical challenges associated with its clinical implementation.

二维剪切波超声弹性成像监测儿童肝移植:最新进展综述。
儿童肝移植(PLT)是一项挽救终末期肝病儿童生命的手术。然而,移植后监测,特别是异体移植纤维化等并发症的诊断和预后仍然具有挑战性。传统上,肝活检一直是评估同种异体移植纤维化的金标准,尽管它具有侵入性和固有的操作风险。最近,剪切波超声弹性成像(SWE)作为一种无创方法,越来越多地用于实时定量测量肝脏硬度,作为纤维化的替代指标。在这篇综述中,介绍了使用SWE作为评估同种异体移植术后纤维化的方法的最新进展,包括目前与临床实施相关的技术挑战。
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来源期刊
Pediatric Transplantation
Pediatric Transplantation 医学-小儿科
CiteScore
2.90
自引率
15.40%
发文量
216
审稿时长
3-8 weeks
期刊介绍: The aim of Pediatric Transplantation is to publish original articles of the highest quality on clinical experience and basic research in transplantation of tissues and solid organs in infants, children and adolescents. The journal seeks to disseminate the latest information widely to all individuals involved in kidney, liver, heart, lung, intestine and stem cell (bone-marrow) transplantation. In addition, the journal publishes focused reviews on topics relevant to pediatric transplantation as well as timely editorial comment on controversial issues.
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