Unraveling EEG correlates of unimanual finger movements: insights from non-repetitive flexion and extension tasks.

Abstract

Background: The loss of finger control in individuals with neuromuscular disorders significantly impacts their quality of life. Electroencephalography (EEG)-based brain-computer interfaces that actuate neuroprostheses directly via decoded motor intentions can help restore lost finger mobility. However, the extent to which finger movements exhibit distinct and decodable EEG correlates remains unresolved. This study aims to investigate the EEG correlates of unimanual, non-repetitive finger flexion and extension.

Methods: Sixteen healthy, right-handed participants completed multiple sessions of right-hand finger movement experiments. These included five individual (Thumb, Index, Middle, Ring, and Pinky) and four coordinated (Pinch, Point, ThumbsUp, and Fist) finger flexions and extensions, along with a rest condition (None). High-density EEG and finger trajectories were simultaneously recorded and analyzed. We examined low-frequency (0.3-3 Hz) time series and movement-related cortical potentials (MRCPs), and event-related desynchronization/synchronization (ERD/S) in the alpha- (8-13 Hz) and beta (13-30 Hz) bands. A clustering approach based on Riemannian distances was used to chart similarities between the broadband EEG responses (0.3-70 Hz) to the different finger scenarios. The contribution of different state-of-the-art features was identified across sub-bands, from low-frequency to low gamma (30-70 Hz), and an ensemble approach was used to pairwise classify single-trial finger movements and rest.

Results: A significant decrease in EEG amplitude in the low-frequency time series was observed in the contralateral frontal-central regions during finger flexion and extension. Distinct MRCP patterns were found in the pre-, ongoing-, and post-movement stages. Additionally, strong ERD was detected in the contralateral central brain regions in both alpha and beta bands during finger flexion and extension, with the beta band showing a stronger rebound (ERS) post-movement. Within the finger movement repertoire, the Thumb was most distinctive, followed by the Fist. Decoding results indicated that low-frequency time-domain amplitude better differentiates finger movements, while alpha and beta band power and Riemannian features better detect movement versus rest. Combining these features yielded over 80% finger movement detection accuracy, while pairwise classification accuracy exceeded 60% for the Thumb versus the other fingers.

Conclusion: Our findings confirm that non-repetitive finger movements, whether individual or coordinated, can be precisely detected from EEG. However, differentiating between specific movements is challenging due to highly overlapping neural correlates in time, spectral, and spatial domains. Nonetheless, certain finger movements, such as those involving the Thumb, exhibit distinct EEG responses, making them prime candidates for dexterous finger neuroprostheses.