Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application

IF 4.5 3区生物学 Q2 CELL BIOLOGY

European journal of cell biology Pub Date : 2024-12-19 DOI:10.1016/j.ejcb.2024.151470

Masanori Kataoka , Takuya Niikawa , Naoya Nagaishi , Tsung-Ling Lee , Alexandre Erler , Julian Savulescu , Tsutomu Sawai

引用次数: 0

Abstract

This study aims to provide a comprehensive review of the ethical, legal and social issues in human brain organoid research, with a view to different types of research and applications: in vitro research, transplantation into non-human animals, and biocomputing. Despite the academic and societal attention on the possibility that human brain organoids may be conscious, we have identified diverse issues in human brain organoid research and applications. To guide the complex terrain of human brain organoid research and applications, a multidisciplinary approach that integrates ethical, legal, and social perspectives is essential.

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超越意识：人类大脑类器官研究和应用中的伦理、法律和社会问题。

本研究旨在全面回顾人类大脑类器官研究中的伦理、法律和社会问题，并着眼于不同类型的研究和应用：体外研究、非人类动物移植和生物计算。尽管学术界和社会关注人类大脑类器官可能具有意识的可能性，但我们已经确定了人类大脑类器官研究和应用中的各种问题。为了指导人类大脑类器官研究和应用的复杂领域，整合伦理、法律和社会观点的多学科方法是必不可少的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European journal of cell biology 生物-细胞生物学

CiteScore

7.30

自引率

1.50%

发文量

审稿时长

38 days

期刊介绍： The European Journal of Cell Biology, a journal of experimental cell investigation, publishes reviews, original articles and short communications on the structure, function and macromolecular organization of cells and cell components. Contributions focusing on cellular dynamics, motility and differentiation, particularly if related to cellular biochemistry, molecular biology, immunology, neurobiology, and developmental biology are encouraged. Manuscripts describing significant technical advances are also welcome. In addition, papers dealing with biomedical issues of general interest to cell biologists will be published. Contributions addressing cell biological problems in prokaryotes and plants are also welcome.