Yuta Nakagawa, Yuto Satake, Masahiro Hata, Manabu Ikeda
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引用次数: 0
Abstract
Temporal lobe epilepsy (TLE) can cause different types of memory impairments. Here, we report a case of immediate improvement of memory impairment following antiepileptic drug (AED) treatment in a patient with TLE with amygdala enlargement (TLE-AE), who rapidly developed recurrence. The patient was a man in his 60s whose family members complained of his amnesia. Neuropsychological investigations detected obvious recent and remote memory loss and executive function impairments. Our examinations revealed evidence of TLE and bilateral amygdala enlargement without any results suggesting organic diseases, resulting in a diagnosis of TLE-AE. Although treatment with levetiracetam immediately improved recent memory and executive function, the improvement of the former was temporary. His recent memory loss impairments recurred within 3 months, but were recovered again after switching drug treatment to lacosamide and suppressing epileptic seizures. Careful follow-up after starting AED and sufficient AED adjustment is important in the treatment of memory problems in TLE-AE.
期刊介绍：
BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.
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