Tea Consumption and Long-Term Mortality in Very Elderly Individuals With or Without Cardiovascular and Cerebrovascular Disease: Findings From a Sample of 19664 Chinese

IF 2.9 3区 医学 Q3 NUTRITION & DIETETICS
Guang-zhi Liao, Man-qing Luo, Xue-mei Zhao, Bo-ping Huang, Yu-hui Zhang, Jian Zhang
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Abstract

Background

The association between tea consumption and mortality among very elderly individuals, with or without cardiovascular and cerebrovascular diseases (CCD), including stroke, remains unclear. This study hypothesised that a significant association exists.

Methods

We analysed data from two waves of the Chinese Longitudinal Healthy Longevity Survey (CLHLS), spanning 1998/2000 to 2018, with a maximum follow-up of 20 years. Cox proportional hazards models, adjusted for potential confounders, were used to examine the association between tea consumption and all-cause mortality among the oldest old ( ≥ 80 years) with or without CCD. Participants were categorised based on the frequency of tea consumption (rare, occasional or regular) at the time of the survey and around the age of 60.

Results

Due to violations of the proportional hazards assumption, Cox model results were reliable only for the first 8 years of follow-up. Among 19,664 elderly participants, frequent tea consumption was associated with a lower mortality risk during the initial 8 years (adjusted HR 0.93, 95% CI 0.89–0.97) compared to never or rare tea consumption. However, this association diminished over the full 20-year follow-up. The significant association was observed only in participants who also reported frequent tea consumption around the age of 60 (adjusted HR 0.91, 95% CI 0.85–0.95). No significant interaction was found between pre-existing CCD and the 8-year effect of tea consumption (P for interaction > 0.05).

Conclusion

Among very elderly Chinese individuals, frequent tea consumption was associated with reduced mortality over the short term, particularly in those who maintained this habit throughout life. No significant interaction effect was observed between pre-existing CCD and the mortality benefits of tea consumption.

饮茶与有或无心脑血管疾病的高龄人群的长期死亡率:来自19664名中国人的调查结果
背景:在患有或不患有心脑血管疾病(CCD)(包括中风)的老年人中,饮茶与死亡率之间的关系尚不清楚。这项研究假设存在显著的关联。方法:我们分析了中国纵向健康寿命调查(CLHLS)的两波数据,时间跨度为1998/2000至2018年,最长随访时间为20年。采用Cox比例风险模型,对潜在混杂因素进行校正,以检验有或无CCD的老年人(≥80岁)饮茶与全因死亡率之间的关系。参与者根据调查时的饮茶频率(罕见、偶尔或经常)和60岁左右的年龄进行分类。结果:由于违反比例风险假设,Cox模型结果仅在随访的前8年是可靠的。在19664名老年参与者中,与从不或很少喝茶相比,在最初的8年里,经常喝茶与较低的死亡风险相关(调整后HR 0.93, 95% CI 0.89-0.97)。然而,在整个20年的随访中,这种关联逐渐减弱。只有在60岁左右经常喝茶的参与者中才观察到显著的关联(调整后危险度0.91,95%可信区间0.85-0.95)。预先存在的CCD与喝茶的8年效应之间没有显著的交互作用(P为交互作用0.05)。结论:在中国的老年人中,经常喝茶与短期内降低死亡率有关,特别是那些终生保持这种习惯的人。未观察到预先存在的CCD与饮茶的死亡率效益之间的显著交互作用。
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来源期刊
CiteScore
5.30
自引率
15.20%
发文量
133
审稿时长
6-12 weeks
期刊介绍: Journal of Human Nutrition and Dietetics is an international peer-reviewed journal publishing papers in applied nutrition and dietetics. Papers are therefore welcomed on: - Clinical nutrition and the practice of therapeutic dietetics - Clinical and professional guidelines - Public health nutrition and nutritional epidemiology - Dietary surveys and dietary assessment methodology - Health promotion and intervention studies and their effectiveness - Obesity, weight control and body composition - Research on psychological determinants of healthy and unhealthy eating behaviour. Focus can for example be on attitudes, brain correlates of food reward processing, social influences, impulsivity, cognitive control, cognitive processes, dieting, psychological treatments. - Appetite, Food intake and nutritional status - Nutrigenomics and molecular nutrition - The journal does not publish animal research The journal is published in an online-only format. No printed issue of this title will be produced but authors will still be able to order offprints of their own articles.
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