Cranio-facial trauma diagnosis using paleo-proteotyping of a blood sample from Robespierre (1794).

IF 1 Q4 PHARMACOLOGY & PHARMACY
Philippe Charlier, Jean Armengaud
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引用次数: 0

Abstract

Tradition has it that the politician Robespierre, a famous tribune of the French Revolution, was lying, wounded in the face by a bullet from a firearm, on an 18th century desk, and left a trace of blood there, before being guillotined the next day (1794). This piece of furniture is now kept in the National Archives (Paris, France). A paleo-proteomic study was carried out on several brown stains on the leather of the desk, which confirmed the human blood nature of the sample, but also identified the protein signature of different cranio-facial organs. This confirms not only the historical anecdote surrounding this desk, but also the importance of contemporary ballistic lesions on the eve of Robespierre's death. This demonstrates the importance and precision of paleo-proteomics in paleopathology and for the examination and identification of the precise nature of stains and micro-traces on old samples.

利用罗伯斯庇尔(1794)血液样本的古蛋白质分型进行颅面创伤诊断。
传统的说法是,政治家罗伯斯庇尔,一位著名的法国大革命论坛官,躺在一张18世纪的桌子上,脸上被一颗枪射出的子弹打伤,在那里留下了血迹,第二天(1794年)被送上了断头台。这件家具现在保存在法国巴黎的国家档案馆。对桌子皮革上的几处棕色污渍进行了古蛋白质组学研究,证实了样本的人类血液性质,同时也鉴定了不同颅面器官的蛋白质特征。这不仅证实了这张桌子周围的历史轶事,也证实了罗伯斯庇尔去世前夕当代弹道损伤的重要性。这证明了古蛋白质组学在古病理学中的重要性和准确性,以及对古老样本上的污渍和微痕迹的精确性质的检查和鉴定。
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来源期刊
Annales pharmaceutiques francaises
Annales pharmaceutiques francaises PHARMACOLOGY & PHARMACY-
CiteScore
1.70
自引率
7.70%
发文量
98
期刊介绍: This journal proposes a scientific information validated and indexed to be informed about the last research works in all the domains interesting the pharmacy. The original works, general reviews, the focusing, the brief notes, subjected by the best academics and the professionals, propose a synthetic approach of the last progress accomplished in the concerned sectors. The thematic Sessions and the – life of the Academy – resume the communications which, presented in front of the national Academy of pharmacy, are in the heart of the current events.
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