Danfeng Ye, Guangrong Zheng, Amjad Ali, Glib V. Baryshnikov, Hans Ågren, Shan Li, Xianzhi Chai, Liangliang Zhu
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引用次数: 0
Abstract
Thermally activated delayed fluorescence (TADF) materials have garnered significant attention as potential candidates for biological photoluminescence imaging. However, the achievement of tunable chiral TADF materials through aggregated and self-assembled processes remains a formidable challenge. In this study, four donor–acceptor–donor type chiral TADF molecules, designed by directly linking electron-donating moieties (phenoxazine, phenothiazine or 1-phenyl-1,2,3,4-tetrahydroisoquinoline) with an electron-acceptor unit (diphenyl sulfone), as promising candidates for luminescent imaging applications are presented. The experimental investigation reveals that these chiral TADF materials possess remarkably small ΔEST values, promoting efficient reverse intersystem crossing (RISC). Additionally, they exhibit aggregation-induced emission and long-delayed luminescent lifetimes affected by the aggregated and self-assembled state. Moreover, deoxygenation significantly enhances the emission, enabling high-contrast hypoxia probing, which shows great potential for high-contrast photoluminescence imaging in living cells. This work not only offers a molecular design strategy for chiral TADF materials but also extends the diverse biological applications of high-contrast hypoxia detection in the biological field.
期刊介绍:
Advanced Optical Materials, part of the esteemed Advanced portfolio, is a unique materials science journal concentrating on all facets of light-matter interactions. For over a decade, it has been the preferred optical materials journal for significant discoveries in photonics, plasmonics, metamaterials, and more. The Advanced portfolio from Wiley is a collection of globally respected, high-impact journals that disseminate the best science from established and emerging researchers, aiding them in fulfilling their mission and amplifying the reach of their scientific discoveries.