Kinetic and Mechanistic Investigation of L-Phenylalanine Oxidation by Alkaline Cu(III) Periodate in CPC Micellar Medium

Abstract

Amino acid oxidation is fascinating because different oxidants produce diverse compounds. No research has examined how metal catalysts affect amino acid oxidation by diperiodatocuprate (III) (DPC) in micellar environments. This research is crucial to understanding amino acids in redox processes and identifying active species of Ru(III) and DPC. The study will evaluate how cationic surfactant affects Ru(III)-facilitated L-phenylalanine (L-Pheala) oxidation utilizing DPC in an alkaline medium. The reaction's advancement has been assessed employing the pseudo-first-order condition as a gauge for [OH⁻], [DPC], ionic strength, [L-Pheala], [Ru(III)], [IO₄⁻], [Surfactant], and temperature. L-Pheala and DPC interact stoichiometrically in a ratio of 1:4. Across the spectrum of concentrations examined, the reported reaction reflects less than unit order kinematics in relation to both [L-Pheala] (0.61 in the aqueous medium and 0.58 in the CPC micellar medium) and [OH⁻] (0.47 in the aqueous medium and 0.51 in the CPC micellar medium), first-order reliance on the [DPC] and [Ru(III)], and negative fractional-order for [IO₄⁻] (−0.54 in the aqueous medium and −0.56 in the CPC micellar medium). A zero salt effect is suggested by the observed constancy in oxidation rate with the inclusion of electrolytes. The oxidation rate is significantly enhanced by Ru(III) solution (as a catalyst) at ppm concentration. Cetylpyridinium chloride (CPC) micellar media facilitate an additional enhancement (four times) in the rate of the reaction. CPC thus exhibits an excellent compatibility with Ru(III) for the L-Pheala oxidation using (DPC).