{"title":"Multimodal autism detection: Deep hybrid model with improved feature level fusion.","authors":"S Vidivelli, P Padmakumari, P Shanthi","doi":"10.1016/j.cmpb.2024.108492","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Social communication difficulties are a characteristic of autism spectrum disorder (ASD), a neurodevelopmental condition. The earlier method of diagnosing autism largely relied on error-prone behavioral observation of symptoms. More intelligence approaches are in progress to diagnose the disorder, which still demands improvement in prediction accuracy. Furthermore, computer-aided design systems based on machine learning algorithms are extremely time-consuming and difficult to design. This study used deep learning techniques to develop a novel autism detection model in order to overcome these problems.</p><p><strong>Methods: </strong>Preprocessing, Features extraction, Improved Feature level Fusion, and Detection are the phases of the suggested autism detection methodology. First, both input modalities will be preprocessed so they are ready for the next stages to be processed. In this case, the facial picture is preprocessed utilizing the Gabor filtering technique, while the input EEG data is preprocessed through Wiener filtering. Subsequently, features are extracted from the modalities, from the EEG signal data, features like Common Spatial Pattern (CSP), Improved Singular Spectrum Entropy, and correlation dimension, are extracted. From the face image, features like the Improved Active Appearance model, Gray-Level Co-occurrence matrix (GLCM) features and Proposed Shape Local Binary Texture (SLBT), as well are retrieved. Following extraction, enhanced feature-level fusion is performed to fuse the features. Ultimately, the combined features are fed into the hybrid model to complete the diagnosis. Models such as Convolutional Neural Networks (CNN) and Bidirectional Gated Recurrent Units (Bi-GRU) are part of the hybrid model.</p><p><strong>Results: </strong>The suggested MADDHM model achieved an accuracy of about 91.03 % regarding EEG and 91.67 % regarding face analysis meanwhile, SVM=87.49 %, DNN=88.59 %, Bi-GRU=90.02 %, LSTM=87.49 % and CNN=82.02 %.</p><p><strong>Conclusion: </strong>As a result, the suggested methodology provides encouraging outcomes and opens up possibilities for early autism detection. The development of such models is not only a technical achievement but also a step forward in providing timely interventions for individuals with ASD.</p>","PeriodicalId":10624,"journal":{"name":"Computer methods and programs in biomedicine","volume":"260 ","pages":"108492"},"PeriodicalIF":4.9000,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer methods and programs in biomedicine","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1016/j.cmpb.2024.108492","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: Social communication difficulties are a characteristic of autism spectrum disorder (ASD), a neurodevelopmental condition. The earlier method of diagnosing autism largely relied on error-prone behavioral observation of symptoms. More intelligence approaches are in progress to diagnose the disorder, which still demands improvement in prediction accuracy. Furthermore, computer-aided design systems based on machine learning algorithms are extremely time-consuming and difficult to design. This study used deep learning techniques to develop a novel autism detection model in order to overcome these problems.
Methods: Preprocessing, Features extraction, Improved Feature level Fusion, and Detection are the phases of the suggested autism detection methodology. First, both input modalities will be preprocessed so they are ready for the next stages to be processed. In this case, the facial picture is preprocessed utilizing the Gabor filtering technique, while the input EEG data is preprocessed through Wiener filtering. Subsequently, features are extracted from the modalities, from the EEG signal data, features like Common Spatial Pattern (CSP), Improved Singular Spectrum Entropy, and correlation dimension, are extracted. From the face image, features like the Improved Active Appearance model, Gray-Level Co-occurrence matrix (GLCM) features and Proposed Shape Local Binary Texture (SLBT), as well are retrieved. Following extraction, enhanced feature-level fusion is performed to fuse the features. Ultimately, the combined features are fed into the hybrid model to complete the diagnosis. Models such as Convolutional Neural Networks (CNN) and Bidirectional Gated Recurrent Units (Bi-GRU) are part of the hybrid model.
Results: The suggested MADDHM model achieved an accuracy of about 91.03 % regarding EEG and 91.67 % regarding face analysis meanwhile, SVM=87.49 %, DNN=88.59 %, Bi-GRU=90.02 %, LSTM=87.49 % and CNN=82.02 %.
Conclusion: As a result, the suggested methodology provides encouraging outcomes and opens up possibilities for early autism detection. The development of such models is not only a technical achievement but also a step forward in providing timely interventions for individuals with ASD.
期刊介绍:
To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine.
Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.