Global collaboration between platform trials in surgery and anaesthesia.

IF 8.6 1区医学 Q1 SURGERY

British Journal of Surgery Pub Date : 2024-11-27 DOI:10.1093/bjs/znae262

James Glasbey, Steve A Webb, Trisha Peel, Thomas D Pinkney, Paul S Myles

引用次数: 0

Abstract

Large, randomized trials are the bedrock of evidence-based medicine, but the resources required to complete such trials greatly limit the number of important clinical questions that can be addressed within a reasonable period of time. Adaptive platform trials can identify effective, ineffective, or harmful treatments faster. These trials have been shown to deliver rapid evidence through the COVID-19 pandemic and are now being adopted across surgery and anaesthesia, with many opportunities for surgeons, anaesthetists, and other perioperative physicians to conduct and collaborate in platform trials.

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大型随机试验是循证医学的基石，但完成此类试验所需的资源极大地限制了在合理时间内解决重要临床问题的数量。自适应平台试验可以更快地确定有效、无效或有害的治疗方法。在 COVID-19 大流行中，这些试验已被证明可以快速提供证据，目前正在外科和麻醉领域广泛采用，外科医生、麻醉师和其他围手术期医生有很多机会开展平台试验并进行合作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

British Journal of Surgery 医学-外科

CiteScore

12.70

自引率

7.30%

发文量

1102

审稿时长

1.5 months

期刊介绍： The British Journal of Surgery (BJS), incorporating the European Journal of Surgery, stands as Europe's leading peer-reviewed surgical journal. It serves as an invaluable platform for presenting high-quality clinical and laboratory-based research across a wide range of surgical topics. In addition to providing a comprehensive coverage of traditional surgical practices, BJS also showcases emerging areas in the field, such as minimally invasive therapy and interventional radiology. While the journal appeals to general surgeons, it also holds relevance for specialty surgeons and professionals working in closely related fields. By presenting cutting-edge research and advancements, BJS aims to revolutionize the way surgical knowledge is shared and contribute to the ongoing progress of the surgical community.