A Facile and Highly Efficient One-Pot Synthesis of Symmetrical and Unsymmetrical Aldazines Using Reusable MMZHY Solid Acid Catalyst

Abstract

A detailed study on one-pot synthesis of 2,3-diaza-1,3-butadiene derivatives from various aromatic aldehydes and hydrazine by using MMZ_HY solid acid catalyst is reported. The role of the bifunctional nature of MMZ_HY and the effect of metal ions in the catalyst are described with a supportive mechanism. Both sym­metrical and unsymmetrical aldazines (hydrazone free) were prepared with excellent yields and characterized by ¹H and ¹³C NMR spectra. The other advantages of the catalytic system like its easy preparation by the bottom-up method, reusability, multiporous nature which reduces diffusional limitations, easy separation, and mild reaction conditions with higher yield of products are also highlighted.