Multidisciplinary unravelling Cogan's syndrome post-C-section: insights into diagnosis, treatment and a possible identified new trigger.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Nataliia Mala, Greta Zweigart, Lukas S Fiedler
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引用次数: 0

Abstract

We present a case series consisting of three female patients in their 30s with presumed autoimmune uveitis resembling Cogan's syndrome following caesarean sections (C-sections) with severe intraoperative bleeding and the use of chitosan-tamponade, exhibiting a combination of varying ocular and auditory symptoms postoperatively. Our patients displayed a range of inflammatory ocular changes, including stromal keratitis, panuveitis, retinal infiltrates, haemorrhages, optic disc swelling, and intraretinal and subretinal fluid, along with otalgia and hearing loss, consistent with typical and atypical Cogan's syndrome. Treatment involved systemic corticosteroids, resulting in variable outcomes. Given the rarity of this disease and its occurrence in similar circumstances, we investigated for a possible common trigger. Vigilance for ocular and auditory symptoms post-C-section, severe blood loss or after the use of chitosan is emphasised, and further research into potential triggers is warranted.

剖宫产后科根综合征的多学科研究:对诊断、治疗和可能确定的新诱因的见解。
我们报告了一个病例系列,包括三名30多岁的女性患者,他们在剖腹产(c -剖宫产)后出现严重的术中出血和壳聚糖填塞,推测其自身免疫性葡萄膜炎类似Cogan综合征,术后表现出不同的眼部和听觉症状。我们的患者表现出一系列眼部炎性改变,包括间质角膜炎、全葡萄膜炎、视网膜浸润、出血、视盘肿胀、视网膜内和视网膜下积液,同时伴有耳痛和听力下降,符合典型和非典型Cogan综合征。治疗涉及全身皮质类固醇,导致不同的结果。鉴于这种疾病的罕见性及其在类似情况下的发生,我们调查了可能的共同触发因素。对剖腹产后、严重失血或使用壳聚糖后的眼部和听觉症状保持警惕,并对潜在的触发因素进行进一步研究是有必要的。
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来源期刊
BMJ Case Reports
BMJ Case Reports Medicine-Medicine (all)
CiteScore
1.40
自引率
0.00%
发文量
1588
期刊介绍: BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.
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