Re-arrest immediately after return of spontaneous circulation: A retrospective observational study of in-hospital cardiac arrest.

IF 1.9 4区 医学 Q2 ANESTHESIOLOGY
Eirik Unneland, Anders Norvik, Daniel Bergum, David G Buckler, Abhishek Bhardwaj, Trygve Christian Eftestøl, Elisabete Aramendi, Trond Nordseth, Benjamin S Abella, Jan Terje Kvaløy, Eirik Skogvoll
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Abstract

Background: Patients who achieve return of spontaneous circulation (ROSC) after in-hospital cardiac arrest (IHCA) may re-arrest. This phenomenon has not been sufficiently investigated. The aim of this study was to examine the immediate (1-min) and short-term (20-min) risks of re-arrest in IHCA.

Methods: We retrospectively analyzed four datasets of IHCA episodes, comprising defibrillator recordings collected between 2002 and 2022. Re-arrest was defined as the resumption of chest compressions following a period of ROSC after cardiac arrest of any duration. Parametric models were applied to calculate the immediate risk of re-arrest. In addition, we estimated the short-term risk of re-arrest within 20 min.

Results: In 763 episodes of IHCA, we observed 316 re-arrests: 68% to pulseless electrical activity (PEA), 25% to ventricular fibrillation/ventricular tachycardia (VF/VT), and 7% to asystole. Most re-arrests occurred with the same rhythm as in the initial arrest. When ROSC was achieved from a non-shockable rhythm, the risk of re-arrest to a non-shockable rhythm was initially 2% per minute and decreased to 1% per minute after 9 min. The corresponding risk of re-arrest to VF/VT was constant at 2% per minute. If ROSC was obtained from a shockable rhythm, the risk of re-arrest to a shockable rhythm was initially 5% per minute, decreasing to 4% per minute after 9 min. The corresponding risk to a non-shockable rhythm was constant at 1% per minute. The risk of re-arrest within 20 min was 27%, and the overall risk of at least one re-arrest per episode was 33%.

Conclusions: The immediate risk of re-arrest was approximately 2% per minute, with the highest risk occurring as a reversion to VF/VT if ROSC was obtained from VF/VT. The risk of re-arrest within 20 min of the initial arrest was 27%, and the overall risk of at least one re-arrest per episode was 33%.

自发循环恢复后立即再骤停:一项住院心脏骤停的回顾性观察研究。
背景:院内心脏骤停(IHCA)后实现自发循环恢复(ROSC)的患者可能再次骤停。这一现象还没有得到充分的研究。本研究的目的是检查IHCA再次骤停的即时(1分钟)和短期(20分钟)风险。方法:我们回顾性分析了2002年至2022年间收集的4个IHCA发作数据集,包括除颤器记录。再骤停定义为在任何持续时间的心脏骤停后一段时间的ROSC后恢复胸外按压。采用参数模型计算再次骤停的即时风险。此外,我们估计了20分钟内再次骤停的短期风险。结果:在763例IHCA发作中,我们观察到316例再停搏:68%为无脉性电活动(PEA), 25%为心室颤动/室性心动过速(VF/VT), 7%为心脏停止。大多数再次被捕的频率与第一次被捕时相同。当从非震荡性心律达到ROSC时,再次骤停至非震荡性心律的风险最初为每分钟2%,9分钟后降至每分钟1%。相应的VF/VT再骤停风险为每分钟2%。如果从可震性心律获得ROSC,再骤停至可震性心律的风险最初为每分钟5%,9分钟后降至每分钟4%。相应的非震荡性心律的风险恒定在每分钟1%。20分钟内再骤停的风险为27%,每集至少一次再骤停的总风险为33%。结论:再骤停的直接风险约为每分钟2%,如果从VF/VT获得ROSC,则恢复到VF/VT的风险最高。初次骤停后20分钟内再骤停的风险为27%,每次发作至少一次再骤停的总风险为33%。
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来源期刊
CiteScore
4.30
自引率
9.50%
发文量
157
审稿时长
3-8 weeks
期刊介绍: Acta Anaesthesiologica Scandinavica publishes papers on original work in the fields of anaesthesiology, intensive care, pain, emergency medicine, and subjects related to their basic sciences, on condition that they are contributed exclusively to this Journal. Case reports and short communications may be considered for publication if of particular interest; also letters to the Editor, especially if related to already published material. The editorial board is free to discuss the publication of reviews on current topics, the choice of which, however, is the prerogative of the board. Every effort will be made by the Editors and selected experts to expedite a critical review of manuscripts in order to ensure rapid publication of papers of a high scientific standard.
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