Ultrasound-assisted condensation cyclization reaction: fast synthesis of quinazolinones from o-aminobenzamides and aldehydes under ambient conditions†

IF 3.4 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
Xuerou Chen, Siqi Li, Shilong Sun and Wuji Sun
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引用次数: 0

Abstract

In this work, a facile and efficient ultrasound-assisted fast synthesis of quinazolinones from o-aminobenzamides and aldehydes is reported. The reaction proceeds smoothly under ambient temperature and pressure conditions without the need for a metal catalyst in just 15 minutes. In addition, this approach exhibits broad substrate tolerance and provides a series of quinazolinones with moderate to excellent yields. The results reported here reveal an important new application of ultrasound-assisted synthesis in the fast synthesis of valuable organic products.

Abstract Image

超声辅助缩合环化反应:在环境条件下从邻氨基苯甲酰胺和醛类快速合成喹唑啉酮类化合物†。
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来源期刊
Reaction Chemistry & Engineering
Reaction Chemistry & Engineering Chemistry-Chemistry (miscellaneous)
CiteScore
6.60
自引率
7.70%
发文量
227
期刊介绍: Reaction Chemistry & Engineering is a new journal reporting cutting edge research into all aspects of making molecules for the benefit of fundamental research, applied processes and wider society. From fundamental, molecular-level chemistry to large scale chemical production, Reaction Chemistry & Engineering brings together communities of chemists and chemical engineers working to ensure the crucial role of reaction chemistry in today’s world.
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