Relevance of macrophages in the wound healing process among individuals afflicted with diabetic foot ulcers.

IF 4.2 3区医学 Q1 ENDOCRINOLOGY & METABOLISM

World Journal of Diabetes Pub Date : 2024-12-15 DOI:10.4239/wjd.v15.i12.2384

Li-Hong Chen, Xing-Wu Ran

引用次数: 0

Abstract

In this paper, we provide a commentary on an article focusing on diabetic foot ulcer (DFU) as a dreadful complication of diabetes mellitus. The development of this condition is influenced by factors such as diabetic peripheral neuropathy, lower extremity artery disease, and infection. However, the underlying mechanism remains elusive. Macrophages play a critical role in wound healing processes, suggesting that therapies targeting these cells could potentially improve the management of DFU. A comprehensive understanding of developmental trends of macrophages within the field of DFU may facilitate research advancements and the development of novel treatment strategies.

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巨噬细胞在糖尿病足溃疡患者伤口愈合过程中的相关性。

在本文中，我们对一篇文章进行了评论，该文章重点讨论了糖尿病足溃疡（DFU）这一糖尿病的可怕并发症。这种疾病的发生受糖尿病周围神经病变、下肢动脉疾病和感染等因素的影响。然而，其根本机制仍然难以捉摸。巨噬细胞在伤口愈合过程中起着至关重要的作用，这表明针对这些细胞的疗法有可能改善对 DFU 的治疗。全面了解巨噬细胞在 DFU 领域的发展动向可能有助于研究进展和新型治疗策略的开发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Diabetes ENDOCRINOLOGY & METABOLISM-

自引率

2.40%

发文量

909

期刊介绍： The WJD is a high-quality, peer reviewed, open-access journal. The primary task of WJD is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of diabetes. In order to promote productive academic communication, the peer review process for the WJD is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJD are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in diabetes. Scope: Diabetes Complications, Experimental Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes, Gestational, Diabetic Angiopathies, Diabetic Cardiomyopathies, Diabetic Coma, Diabetic Ketoacidosis, Diabetic Nephropathies, Diabetic Neuropathies, Donohue Syndrome, Fetal Macrosomia, and Prediabetic State.