A 7-year study of workplace drug testing in two major cities in Türkiye.

IF 1.1 4区 医学 Q4 SUBSTANCE ABUSE
Rukiye Aslan, Duygu Yesim Ovat, Asli Atasoy Aydin, Ismail Ethem Goren, Yusuf Kurtulmus, Inci Saglam, Cengiz Cengisiz, Nebile Daglioglu, Serap Annette Akgur
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Abstract

Background: Workplace Drug Testing (WDT) is a worldwide practice that is crucial in anti-drug efforts. This study aimed to provide compherensive information about the WDT applications in Türkiye with data obtained from two major cities in two different regions of Türkiye.

Methods: The retrospective assessment of forensic toxicological analysis results in urine, hair or urine&hair samples collected from 220 WDT cases in İzmir (3rd largest city) and Adana (5th largest city) from 2016 to 2022 years was carried. The screening and confirmation analysis were performed with immunoassay and liquid chromatography-tandem mass spectrometry (LC-MS/MS), respectively.

Results: Cases with a positive result from one of urine or hair tests were accepted as positive. 20.5% (n = 45) of the cases were detected positive, and most applicants were identified as drivers (84.4%, n = 38). Urine samples of 23.5% (n = 52) were screened by immunoassay, and THC (n = 1) and opiate (n = 1) were detected. In the LC-MS/MS analysis, benzodiazepines were detected most in urine as a single substance, while cannabinoids and codeine were detected in the hair. Multidrug combinations used in treatment were detected in urine and hair. It was detected both alone and among the substances accompanying cannabinoids and amphetamines.

Conclusions: This study presents 7-year WDT results of two different major cities in Türkiye. The method of WDT application differs across the country so a standard procedure should be performed. In our country, where zero tolerance against substance use is adopted, the detection of illegal and controlled substances in cases clearly shows that WDT practice should be routinized.

背景:工作场所毒品检测(WDT)是一种世界性的做法,在禁毒工作中至关重要。本研究旨在通过从土耳其两个不同地区的两个主要城市获得的数据,提供有关土耳其工作场所毒品检测应用的综合信息:方法:对伊兹密尔(第三大城市)和阿达纳(第五大城市)从 2016 年至 2022 年收集的 220 例 WDT 案件的尿液、毛发或尿液和毛发样本的法医毒理学分析结果进行了回顾性评估。筛查和确认分析分别采用免疫测定法和液相色谱-串联质谱法(LC-MS/MS)进行:结果:尿液或毛发检测结果呈阳性的病例被认定为阳性。其中 20.5%(45 人)的检测结果呈阳性,大多数申请人被确定为司机(84.4%,38 人)。23.5%(52 人)的尿液样本经免疫测定法检测,检出四氢大麻酚(1 人)和阿片剂(1 人)。在 LC-MS/MS 分析中,苯并二氮杂卓作为单一物质在尿液中的检出率最高,而大麻素和可待因则在毛发中检出。在尿液和毛发中检测到了用于治疗的多种药物组合。既可单独检测到可待因,也可在大麻素和苯丙胺的伴随物质中检测到可待因:本研究介绍了土耳其两个不同大城市的 7 年 WDT 结果。全国各地使用 WDT 的方法各不相同,因此应执行标准程序。我国对药物使用采取零容忍政策,在病例中检测出非法和受管制药物的情况清楚地表明,WDT 的做法应常规化。
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来源期刊
CiteScore
3.20
自引率
7.70%
发文量
50
期刊介绍: The Journal of Ethnicity in Substance Abuse presents rigorous new studies and research on ethnicity and cultural variation in alcohol, tobacco, licit and illicit forms of substance use and abuse. The research is drawn from many disciplines and interdisciplinary areas in the social and behavioral sciences, public health, and helping professions. The Journal of Ethnicity in Substance Abuse is an international forum for identification of emergent and culturally diverse substance use and abuse trends, and the implementation of culturally competent strategies in harm reduction, individual, group, and family treatment of substance abuse. The Journal systematically investigates the beliefs, attitudes, and values of substance abusers, searching for the answers to the origins of drug use and abuse for different ethnic groups. The Journal publishes research papers, review papers, policy commentaries, and conference proceedings. The Journal welcomes submissions from across the globe, and strives to ensure efficient review and publication outcomes.
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