Spatiotemporal spinal cord stimulation with real-time triggering exoskeleton restores walking capability: a case report

IF 4.4 2区医学 Q1 CLINICAL NEUROLOGY

Annals of Clinical and Translational Neurology Pub Date : 2024-12-15 DOI:10.1002/acn3.52281

Penghao Liu, Yuanchen Cheng, Zhuofan Xu, Xiaoyu Li, Zan Chen, Wanru Duan

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引用次数: 0

Abstract

Objective

Motor recovery is challenging for spinal cord injury (SCI), especially in low-level SCI.

Methods

A 16-year-old patient with complete SCI at T12 presented flaccid paralysis and inability to control defecation and was scored as ASIA A at admission. The patient underwent spinal cord stimulation (SCS) implantation at the T11-L1, followed by an innovative algorithm combining spatiotemporal SCS with real-time triggered exoskeleton training (EXS-SCS).

Results

After 1 month of treatment, she gained substantial improvement in her iliopsoas and quadriceps femoris muscle strength to grade 3–4 as well as percutaneous EMG, allowing for assisted standing and walking, and was reassessed as ASIA C.

Interpretation

This case reveals the potential of SCS-EXS regimen in restoring walking capability of SCI patients.

Abstract Image

查看原文本刊更多论文

时空脊髓刺激与实时触发外骨骼恢复行走能力：一个案例报告。

目的脊髓损伤（SCI）的运动恢复具有挑战性，尤其是低位 SCI：一名16岁的患者因T12完全性SCI而出现弛缓性瘫痪，无法控制排便，入院时被评为ASIA A级。患者接受了T11-L1脊髓刺激（SCS）植入术，随后接受了结合时空SCS和实时触发外骨骼训练（EXS-SCS）的创新算法：治疗 1 个月后，她的髂腰肌和股四头肌肌力大幅改善，达到 3-4 级，经皮肌电图也得到改善，可以辅助站立和行走，并被重新评估为 ASIA C 级：本病例揭示了 SCS-EXS 方案在恢复 SCI 患者行走能力方面的潜力。

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来源期刊

Annals of Clinical and Translational Neurology Medicine-Neurology (clinical)

CiteScore

9.10

自引率

1.90%

发文量

218

审稿时长

8 weeks

期刊介绍： Annals of Clinical and Translational Neurology is a peer-reviewed journal for rapid dissemination of high-quality research related to all areas of neurology. The journal publishes original research and scholarly reviews focused on the mechanisms and treatments of diseases of the nervous system; high-impact topics in neurologic education; and other topics of interest to the clinical neuroscience community.