Early onset pancreatic cancer: A review.

IF 4.5 2区医学 Q1 ONCOLOGY

Translational Oncology Pub Date : 2024-12-11 DOI:10.1016/j.tranon.2024.102239

Dong Luo, Yixiong Li, Xiao Yu, Liandong Ji, Xuejun Gong

引用次数: 0

Abstract

Early-onset pancreatic cancer (EOPC) is usually defined as patients with pancreatic cancer before the age of 50 years, which is relatively rare. However, the research on EOPC is somewhat obscure, and the specific clinical and molecular characteristics of this condition are debated. In this review, we discussed the differences between EOPC and late-onset pancreatic cancer (LOPC) or average-onset pancreatic cancer (AOPC) with a focus on clinical and molecular characteristics, survival outcomes and treatment to promote the diagnosis and treatment of EOPC.

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早发胰腺癌：综述。

早发胰腺癌（EOPC）通常是指 50 岁之前罹患胰腺癌的患者，这种情况相对罕见。然而，关于早发胰腺癌的研究还有些模糊，对其具体的临床和分子特征也存在争议。在这篇综述中，我们讨论了EOPC与晚发性胰腺癌（LOPC）或平均发性胰腺癌（AOPC）的区别，重点关注临床和分子特征、生存结果和治疗方法，以促进EOPC的诊断和治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Translational Oncology Biochemistry, Genetics and Molecular Biology-Cancer Research

CiteScore

7.20

自引率

2.00%

发文量

314

审稿时长

6-12 weeks

期刊介绍： Translational Oncology publishes the results of novel research investigations which bridge the laboratory and clinical settings including risk assessment, cellular and molecular characterization, prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of oncology patients. Translational Oncology will publish laboratory studies of novel therapeutic interventions as well as clinical trials which evaluate new treatment paradigms for cancer. Peer reviewed manuscript types include Original Reports, Reviews and Editorials.