Detection of Parkinson's disease using nocturnal breathing signals based on multifractal detrended fluctuation analysis.

IF 2.7 2区 数学 Q1 MATHEMATICS, APPLIED
Chaos Pub Date : 2024-12-01 DOI:10.1063/5.0237878
Zhong Dai, Shutang Liu, Changan Liu
{"title":"Detection of Parkinson's disease using nocturnal breathing signals based on multifractal detrended fluctuation analysis.","authors":"Zhong Dai, Shutang Liu, Changan Liu","doi":"10.1063/5.0237878","DOIUrl":null,"url":null,"abstract":"<p><p>Parkinson's disease (PD) is a highly prevalent neurodegenerative disorder that poses a significant challenge in terms of accurate and cost-effective diagnosis. This study focuses on the use of fractal features derived from nocturnal breathing signals to diagnose PD. Our study includes 49 individuals with Parkinson's disease (PD group), 49 relatively healthy individuals without PD (HC group), 49 individuals without PD but with other diseases (NoPD group), as well as 12 additional PD patients and 200 healthy individuals for testing. Using multifractal detrended fluctuation analysis, we extracted fractal features from nocturnal breathing signals, with logistic regression models applied to diagnose PD, as demonstrated in receiver operating characteristic curves. Eight fractal features show significant diagnostic potential for PD, including generalized Hurst exponents for the Airflow, Thorax, and Abdomen signals and the multifractal spectrum width of the SaO2 signal. Finally, the area under the receiver operating characteristic curve (AUC) of the training data set of the PD and HC groups for all four signals is 0.911, and the AUC of the testing data set is 0.929. These results demonstrate the potential of this work to enhance the accuracy of PD diagnosis in clinical settings.</p>","PeriodicalId":9974,"journal":{"name":"Chaos","volume":"34 12","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chaos","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1063/5.0237878","RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATHEMATICS, APPLIED","Score":null,"Total":0}
引用次数: 0

Abstract

Parkinson's disease (PD) is a highly prevalent neurodegenerative disorder that poses a significant challenge in terms of accurate and cost-effective diagnosis. This study focuses on the use of fractal features derived from nocturnal breathing signals to diagnose PD. Our study includes 49 individuals with Parkinson's disease (PD group), 49 relatively healthy individuals without PD (HC group), 49 individuals without PD but with other diseases (NoPD group), as well as 12 additional PD patients and 200 healthy individuals for testing. Using multifractal detrended fluctuation analysis, we extracted fractal features from nocturnal breathing signals, with logistic regression models applied to diagnose PD, as demonstrated in receiver operating characteristic curves. Eight fractal features show significant diagnostic potential for PD, including generalized Hurst exponents for the Airflow, Thorax, and Abdomen signals and the multifractal spectrum width of the SaO2 signal. Finally, the area under the receiver operating characteristic curve (AUC) of the training data set of the PD and HC groups for all four signals is 0.911, and the AUC of the testing data set is 0.929. These results demonstrate the potential of this work to enhance the accuracy of PD diagnosis in clinical settings.

求助全文
约1分钟内获得全文 求助全文
来源期刊
Chaos
Chaos 物理-物理:数学物理
CiteScore
5.20
自引率
13.80%
发文量
448
审稿时长
2.3 months
期刊介绍: Chaos: An Interdisciplinary Journal of Nonlinear Science is a peer-reviewed journal devoted to increasing the understanding of nonlinear phenomena and describing the manifestations in a manner comprehensible to researchers from a broad spectrum of disciplines.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信