{"title":"Rapid detection and classification of pharmaceutical molecules using Ag/ZIF-8/TNTs composite substrate","authors":"Jinmei Chen, Yudong Lu, Chunling Xie, Xiufeng Xiao","doi":"10.1016/j.saa.2024.125566","DOIUrl":null,"url":null,"abstract":"<div><div>Discarded drugs in the ecosystem pose a significant threat to human health and are a global health problem. Therefore, it is essential to establish effective detection and degradation strategies. Metal-organic framework ZIF-8 and Ag NPs were separately grown on titanium dioxide nanotube arrays (TNTs), resulting in the successful synthesis of cost-effective Ag/ZIF-8/TNTs composite substrates. These substrates were able to detect methylene blue (MB) at a low concentration of 1 × 10<sup>−13</sup> M, with a surface-enhanced Raman scattering (SERS) analysis enhancement factor (AEF) of 1.4 × 10<sup>7</sup>, which was higher than other similar substrates. Importantly, the device exhibited high sensitivity and accuracy for rapid detection and classification. Furthermore, this device successfully detected and classified Ibuprofen, Vancomycin, and Doxorubicin with 100 % accuracy using their SERS signatures. Additionally, the Ag/ZIF-8/TNTs substrates showed excellent photocatalytic degradation capability and could be reused without significant loss in activity after five cycles of use. The dual-functional Ag/ZIF-8/TNTs substrates were cost-effective and efficient for the detection and treatment of pollutants in wastewater.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"329 ","pages":"Article 125566"},"PeriodicalIF":4.3000,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1386142524017323","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SPECTROSCOPY","Score":null,"Total":0}
引用次数: 0
Abstract
Discarded drugs in the ecosystem pose a significant threat to human health and are a global health problem. Therefore, it is essential to establish effective detection and degradation strategies. Metal-organic framework ZIF-8 and Ag NPs were separately grown on titanium dioxide nanotube arrays (TNTs), resulting in the successful synthesis of cost-effective Ag/ZIF-8/TNTs composite substrates. These substrates were able to detect methylene blue (MB) at a low concentration of 1 × 10−13 M, with a surface-enhanced Raman scattering (SERS) analysis enhancement factor (AEF) of 1.4 × 107, which was higher than other similar substrates. Importantly, the device exhibited high sensitivity and accuracy for rapid detection and classification. Furthermore, this device successfully detected and classified Ibuprofen, Vancomycin, and Doxorubicin with 100 % accuracy using their SERS signatures. Additionally, the Ag/ZIF-8/TNTs substrates showed excellent photocatalytic degradation capability and could be reused without significant loss in activity after five cycles of use. The dual-functional Ag/ZIF-8/TNTs substrates were cost-effective and efficient for the detection and treatment of pollutants in wastewater.
期刊介绍:
Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (SAA) is an interdisciplinary journal which spans from basic to applied aspects of optical spectroscopy in chemistry, medicine, biology, and materials science.
The journal publishes original scientific papers that feature high-quality spectroscopic data and analysis. From the broad range of optical spectroscopies, the emphasis is on electronic, vibrational or rotational spectra of molecules, rather than on spectroscopy based on magnetic moments.
Criteria for publication in SAA are novelty, uniqueness, and outstanding quality. Routine applications of spectroscopic techniques and computational methods are not appropriate.
Topics of particular interest of Spectrochimica Acta Part A include, but are not limited to:
Spectroscopy and dynamics of bioanalytical, biomedical, environmental, and atmospheric sciences,
Novel experimental techniques or instrumentation for molecular spectroscopy,
Novel theoretical and computational methods,
Novel applications in photochemistry and photobiology,
Novel interpretational approaches as well as advances in data analysis based on electronic or vibrational spectroscopy.