Effect of exercise on quality of life in people with chronic obstructive pulmonary disease: A network meta-analysis of RCTs

IF 3.9 3区医学 Q1 REHABILITATION

Annals of Physical and Rehabilitation Medicine Pub Date : 2024-12-12 DOI:10.1016/j.rehab.2024.101890

Susana Priego-Jiménez , Maribel Lucerón-Lucas-Torres , Patricia Lorenzo-García , Marta González-Molinero , Alberto Bermejo-Cantarero , Celia Álvarez-Bueno

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引用次数: 0

Abstract

Background

Chronic obstructive pulmonary disease (COPD) is characterized by a gradual deterioration of respiratory capacity, with worsening fatigue, weakness, activity intolerance, and dyspnea, influencing the person's emotional state and quality of life (QoL).

Objective

A network meta-analysis (NMA) was performed to determine the effects of different physical activity interventions on overall QoL in people with COPD, followed by a meta-analysis on the effect of these interventions on the different domains of the QoL scales.

Methods

A literature search was performed from inception to December 2023. Randomized controlled trials on the effectiveness of exercise programs on QoL in people with COPD were included. We assessed the risk of bias using the Cochrane Risk of Bias (RoB 2.0) tool and used the Grading of Recommendations, Assessment, Development, and Evaluation tool (GRADE) to assess the quality of the evidence. Pairwise meta-analysis and NMA for direct and indirect evidence were performed.

Results

A total of 54 studies were included in the NMA. The largest effects were for active mind-body movement therapy (AMBMT) programs versus control interventions (usual practice) for total QoL (effect size [ES] 0.87; 95 % CI 0.65–1.09), followed by endurance (END) vs control (ES 0.75; 95 % CI 0.27–1.24) and combined (COMB) versus control (ES 0.73; 95 % CI 0.02–1.43). The results reflected an improvement in all subdomains of the QoL scales, except for social support.

Conclusions

AMBMT should be considered the most effective strategy to improve overall QoL in people with COPD, followed by END and COMB interventions. Physical activity interventions produce a positive effect in all the QoL domains studied, except for social support.

PROSPERO registration number

CRD42023393463.

查看原文本刊更多论文

运动对慢性阻塞性肺疾病患者生活质量的影响：随机对照试验的网络荟萃分析

背景：慢性阻塞性肺疾病（COPD）以呼吸能力逐渐恶化为特征，伴有疲劳、无力、活动不耐受和呼吸困难的加重，影响患者的情绪状态和生活质量（QoL）。目的：通过网络荟萃分析（NMA）确定不同体育活动干预对COPD患者总体生活质量的影响，然后对这些干预对生活质量量表不同领域的影响进行荟萃分析。方法：从成立到2023年12月进行文献检索。纳入了关于运动项目对慢性阻塞性肺病患者生活质量影响的随机对照试验。我们使用Cochrane风险偏倚（RoB 2.0）工具评估偏倚风险，并使用分级推荐、评估、发展和评价工具（GRADE）评估证据质量。对直接和间接证据进行两两荟萃分析和NMA。结果：NMA共纳入54项研究。对总生活质量影响最大的是主动身心运动疗法（AMBMT）方案与对照干预（常规做法）(效应量[ES] 0.87；95% CI 0.65-1.09)，其次是耐力（END） vs对照组(ES 0.75；95% CI 0.27-1.24)和联合（COMB）与对照组(ES 0.73；95% ci 0.02-1.43)。结果表明，除了社会支持外，生活质量量表的所有子领域都有所改善。结论：AMBMT应被认为是改善COPD患者总体生活质量的最有效策略，其次是END和COMB干预。除了社会支持外，体育活动干预在所有研究的生活质量领域都产生积极影响。普洛斯彼罗注册号：CRD42023393463。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Physical and Rehabilitation Medicine Medicine-Rehabilitation

CiteScore

7.80

自引率

4.30%

发文量

136

审稿时长

34 days

期刊介绍： Annals of Physical and Rehabilitation Medicine covers all areas of Rehabilitation and Physical Medicine; such as: methods of evaluation of motor, sensory, cognitive and visceral impairments; acute and chronic musculoskeletal disorders and pain; disabilities in adult and children ; processes of rehabilitation in orthopaedic, rhumatological, neurological, cardiovascular, pulmonary and urological diseases.