Investigating the impact of the effective point of measurement for plane-parallel ionization chambers in clinical proton beams.

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Kilian-Simon Baumann, Ana Lourenço, Jörg Wulff, Gloria Vilches-Freixas, Hugo Palmans
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引用次数: 0

Abstract

Objective: To investigate the impact of the positioning of plane-parallel ionization chambers in proton beams on the calculation of the chamber-specific factor fQand, hence, the beam quality correction factor kQ,Q0. Approach: Monte Carlo simulations were performed to calculate the chamber-specific factor fQin monoenergetic proton beams for six different plane-parallel ionization chambers while positioning the chambers with a) their reference point and b) their effective point of measurement accounting for the water equivalent thickness of the entrance window. Main results: For all ionization chamber models investigated in this study, the difference in fQbetween both positioning approaches was larger for steeper dose gradients and bigger differences between the geometrical thickness and water-equivalent thickness of the entrance window. The largest effect was 1.2% for the IBA PPC-05 ionization chamber at an energy of 60 MeV. Significance: The positioning of plane-parallel ionization chambers in proton beams has a systematic impact on the fQfactor. This is especially of relevance for the kQ,Q0factors presented in the recently updated TRS-398 Code of Practice (CoP) from IAEA. The background is that a positioning with the effective point of measurement is prescribed in TRS-398 CoP, however, all Monte Carlo derived data that have been employed for the update are based on a positioning of the ionization chambers with their reference point. Hence, the updated kQ,Q0factors for plane-parallel ionization chambers in proton beams are subject to systematic errors that are as large as 0.5%. .

目的:研究质子束中平面平行电离室的定位对计算室专用系数 fQ 的影响,进而影响束质量校正系数 kQ,Q0:进行蒙特卡罗模拟,计算六种不同平面平行电离室在单能质子束中的电离室特定因子 fQ,同时将电离室定位在 a) 参考点和 b) 有效测量点,并考虑入口窗口的水等效厚度:对于本研究调查的所有电离室模型,如果剂量梯度较陡,入口窗口的几何厚度和水当量厚度差异较大,则两种定位方法的 fQ 差异较大。能量为 60 MeV 时,IBA PPC-05 电离室的最大影响为 1.2%:质子束中平面平行电离室的定位对 fQ 因子有系统性影响。这与国际原子能机构(IAEA)最近更新的 TRS-398 操作规范(CoP)中提出的 kQ、Q0 因子尤其相关。其背景是,TRS-398 工作守则规定了有效测量点的定位,但所有用于更新的蒙特卡洛推导数据都是基于电离室与参考点的定位。因此,质子束中平面平行电离室的 kQ,Q0 因子的更新系统误差高达 0.5%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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