{"title":"An efficient deep unrolling network for sparse-view CT reconstruction via alternating optimization of dense-view sinograms and images.","authors":"Chang Sun, Yitong Liu, Hongwen Yang","doi":"10.1088/1361-6560/ad9dac","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>There have been many advancements in deep unrolling methods for sparse-view computed tomography (SVCT) reconstruction. These methods combine model-based and deep learning-based reconstruction techniques, improving the interpretability and achieving significant results. However, they are often computationally expensive, particularly for clinical raw projection data with large sizes. This study aims to address this issue while maintaining the quality of the reconstructed image.</p><p><strong>Approach: </strong>The SVCT reconstruction task is decomposed into two subproblems using the proximal gradient method: optimizing dense-view sinograms and optimizing images. Then dense-view sinogram inpainting, image-residual learning, and image-refinement modules are performed at each iteration stage using deep neural networks. Unlike previous unrolling methods, the proposed method focuses on optimizing dense-view sinograms instead of full-view sinograms. This approach not only reduces computational resources and runtime but also minimizes the challenge for the network to perform sinogram inpainting when the sparse ratio is extremely small, thereby decreasing the propagation of estimation error from the sinogram domain to the image domain.</p><p><strong>Main results: </strong>The proposed method successfully reconstructs an image (512×512 pixels) from real-size (2304×736) projection data, with 3.39 M training parameters and an inference time of 0.09 seconds per slice on a GPU. The proposed method also achieves superior quantitative and qualitative results compared with state-of-the-art deep unrolling methods on datasets with sparse ratios of 1/12 and 1/18, especially in suppressing artifacts and preserving structural details. Additionally, results show that using dense-view sinogram inpainting not only accelerates the computational speed but also leads to faster network convergence and further improvements in reconstruction results.</p><p><strong>Significance: </strong>This research presents an efficient dual-domain deep unrolling technique that produces excellent results in SVCT reconstruction while requiring small computational resources. These findings have important implications for speeding up deep unrolling CT reconstruction methods and making them more practical for processing clinical CT projection data.</p>","PeriodicalId":20185,"journal":{"name":"Physics in medicine and biology","volume":" ","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics in medicine and biology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1088/1361-6560/ad9dac","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: There have been many advancements in deep unrolling methods for sparse-view computed tomography (SVCT) reconstruction. These methods combine model-based and deep learning-based reconstruction techniques, improving the interpretability and achieving significant results. However, they are often computationally expensive, particularly for clinical raw projection data with large sizes. This study aims to address this issue while maintaining the quality of the reconstructed image.
Approach: The SVCT reconstruction task is decomposed into two subproblems using the proximal gradient method: optimizing dense-view sinograms and optimizing images. Then dense-view sinogram inpainting, image-residual learning, and image-refinement modules are performed at each iteration stage using deep neural networks. Unlike previous unrolling methods, the proposed method focuses on optimizing dense-view sinograms instead of full-view sinograms. This approach not only reduces computational resources and runtime but also minimizes the challenge for the network to perform sinogram inpainting when the sparse ratio is extremely small, thereby decreasing the propagation of estimation error from the sinogram domain to the image domain.
Main results: The proposed method successfully reconstructs an image (512×512 pixels) from real-size (2304×736) projection data, with 3.39 M training parameters and an inference time of 0.09 seconds per slice on a GPU. The proposed method also achieves superior quantitative and qualitative results compared with state-of-the-art deep unrolling methods on datasets with sparse ratios of 1/12 and 1/18, especially in suppressing artifacts and preserving structural details. Additionally, results show that using dense-view sinogram inpainting not only accelerates the computational speed but also leads to faster network convergence and further improvements in reconstruction results.
Significance: This research presents an efficient dual-domain deep unrolling technique that produces excellent results in SVCT reconstruction while requiring small computational resources. These findings have important implications for speeding up deep unrolling CT reconstruction methods and making them more practical for processing clinical CT projection data.
期刊介绍:
The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry