Sarah E Park, Elaine Ma, Caitlyn Dagenet, Maria A Aleshin, Heather M Holahan, Vivian Y Shi, Jennifer L Hsiao
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引用次数: 0
Abstract
Introduction: Chronic urticaria (CU) is frequently a debilitating skin condition characterized by recurrent and spontaneous wheal and flares with significant impact on quality of life. This systematic review examines the impact of CU on sexual health.
Methods: A systematic review using PubMed, Embase, Web of Science, and Cochrane library databases was conducted for articles on sexual health in chronic urticaria.
Results: The database search produced 741 articles, of which 14 articles met inclusion criteria. Study design, patient demographics, disease characteristics, measures used to assess sexuality or sexual function, and study results were independently extracted for each article by two researchers. Any discrepancies were resolved to consensus by a third reviewer. Sexual dysfunction was common in patients with CU and its severity is associated with increased disease activity and poor disease control.
Conclusion: Sexual dysfunction is common in patients with CU, and it negatively affects their quality of life (QoL), body image, sleep quality, and mental health. Incorporating sexual health assessments into CU trials will allow for valuable insights into efficacy of study medications on this important QoL domain. Increased awareness of sexual impairment in CU is needed to provide comprehensive care.
期刊介绍:
Dermatology and Therapy is an international, open access, peer-reviewed, rapid publication journal (peer review in 2 weeks, published 3–4 weeks from acceptance). The journal is dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of dermatological therapies. Studies relating to diagnosis, pharmacoeconomics, public health and epidemiology, quality of life, and patient care, management, and education are also encouraged.
Areas of focus include, but are not limited to all clinical aspects of dermatology, such as skin pharmacology; skin development and aging; prevention, diagnosis, and management of skin disorders and melanomas; research into dermal structures and pathology; and all areas of aesthetic dermatology, including skin maintenance, dermatological surgery, and lasers.
The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports/case series, trial protocols, and short communications. Dermatology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an International and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of quality research, which may be considered of insufficient interest by other journals. The journal appeals to a global audience and receives submissions from all over the world.