EXPRESSION OF CONCERN: The Truncated Human Telomeric Sequence Forms a Hybrid-Type Intramolecular Mixed Parallel/antiparallel G-quadruplex Structure in K+ Solution

Abstract

EXPRESSION OF CONCERN: Y. Liu, D. Cheng, M. Ge, and W. Lin, “The Truncated Human Telomeric Sequence Forms a Hybrid-Type Intramolecular Mixed Parallel/antiparallel G-quadruplex Structure in K+ Solution,” Chemical Biology & Drug Design 88, no. 1 (2016): 122-128, https://doi.org/10.1111/cbdd.12740.

This Expression of Concern is for the above article, published online on 12 February 2016, in Wiley Online Library (http://onlinelibrary.wiley.com/), and has been issued by agreement between the journal Editor-in-Chief, Roberta Melander; and John Wiley & Sons Ltd. A third party reported to the publisher that the gel-shift assay image in Figure 2 shows evidence of splicing. Further analysis by the publisher has confirmed the evidence of splicing. The authors responded to an inquiry by the publisher but stated that the original data were no longer available. The authors also stated that they had adjusted the brightness levels in the gel images used in this article, but did not alter experimental results. The Expression of Concern has been agreed to because the journal and publisher agree that Figure 2 contains spliced lanes and as a result, they are not able to confirm the veracity of the experiments described in this article. The authors disagree with the Expression of Concern.