The projected burden of arthritis among adults and children in Australia to the year 2040: a population-level forecasting study.

IF 15 1区 医学 Q1 RHEUMATOLOGY
Ilana N Ackerman, Alexandra Gorelik, Danielle Berkovic, Rachelle Buchbinder
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引用次数: 0

Abstract

Background: Understanding how many people could be living with arthritis in the future is essential for planning health service needs and national health workforce requirements, and for arthritis advocacy and policy development. This study aimed to forecast the size of different populations with arthritis in Australia and associated health system expenditure, up to the year 2040.

Methods: In this population-level forecasting study for Australia, prevalence data for arthritis, osteoarthritis, and rheumatoid arthritis were obtained from the Australian Bureau of Statistics 2022 National Health Survey. Prevalence rates for juvenile idiopathic arthritis were sourced from 2021 Census data. Overall, age-specific and sex-specific prevalence data were applied to national population projections to forecast arthritis, osteoarthritis, rheumatoid arthritis, and juvenile idiopathic arthritis populations for 2025, 2030, 2035, and 2040. The base case analysis considered medium population growth; sensitivity analyses considered low and high growth scenarios. Health system expenditure data from the Australian Institute of Health and Welfare were extrapolated to base case projections for the years 2025, 2030, 2035, and 2040, and were then inflated to future dollars. To understand the broader context and implications of our projections through the lens of lived experience, an arthritis consumer researcher and members of the Arthritis Australia Consumer Advisory Panel reviewed the arthritis burden estimates.

Findings: With population growth and ageing, 5·39 million (95% CI 5·19-5·58) people are projected to have arthritis in Australia in 2040, representing an increase of 31% from 4·11 million (3·95-4·27) in 2025. By 2040, 3·11 million (2·99-3·23) people are expected to have osteoarthritis, 749 000 (652 000-846 000) are expected to have rheumatoid arthritis, and about 8500 children and adolescents are expected to have juvenile idiopathic arthritis. The age-standardised rate of osteoarthritis is forecast to increase for males from 6·28% in 2025 to 7·03% in 2040, and for females from 10·82% to 12·18% over this period. The age-standardised rate of rheumatoid arthritis is forecast to increase for males from 1·56% in 2025 to 1·75% in 2040, and for females from 2·62% in 2025 to 2·94% in 2040. Little change is anticipated in the number of children and adolescents with juvenile idiopathic arthritis (estimated at 8500 individuals in 2040). Based on current spending levels of AU$2100 per person with osteoarthritis and $1918 per person with rheumatoid arthritis, annual health system expenditure for osteoarthritis and rheumatoid arthritis is conservatively forecast to exceed AU$11·92 billion by 2040.

Interpretation: Using the latest national-level data, this study has generated contemporary projections of the substantial burden of arthritis (both population size and health-care costs) in Australia. These projections underscore the importance of well-resourced health services that can capably deliver timely, high-value care to a growing number of people with arthritis.

Funding: Arthritis Australia and National Health and Medical Research Council.

到 2040 年澳大利亚成人和儿童中关节炎的预计负担:人口预测研究。
背景:了解未来可能会有多少人患有关节炎,对于规划医疗服务需求和国家医疗人员需求,以及关节炎的宣传和政策制定都至关重要。这项研究旨在预测到 2040 年澳大利亚不同关节炎患者的规模以及相关的医疗系统支出:在这项澳大利亚人口预测研究中,关节炎、骨关节炎和类风湿性关节炎的患病率数据来自澳大利亚统计局 2022 年全国健康调查。幼年特发性关节炎的患病率来自 2021 年人口普查数据。总体而言,特定年龄和特定性别的患病率数据被应用于全国人口预测,以预测 2025 年、2030 年、2035 年和 2040 年的关节炎、骨关节炎、类风湿性关节炎和幼年特发性关节炎患病人数。基础分析考虑了中等人口增长;敏感性分析考虑了低增长和高增长情景。澳大利亚卫生与福利研究所提供的卫生系统支出数据被推断为 2025 年、2030 年、2035 年和 2040 年的基础预测值,然后膨胀为未来的美元。为了从生活经验的角度来理解我们的预测的更广泛背景和影响,一位关节炎消费者研究员和澳大利亚关节炎消费者顾问小组成员对关节炎负担估算进行了审查:随着人口增长和老龄化的加剧,预计到2040年,澳大利亚将有500-3900万(95% CI 5-19-5-58)人患有关节炎,比2025年的400-1100万(3-95-4-27)人增加了31%。到2040年,预计有300-1100万人(2-99-3-23)患有骨关节炎,749000人(652000-846000)患有类风湿性关节炎,约8500名儿童和青少年患有幼年特发性关节炎。预计在此期间,男性骨关节炎的年龄标准化发病率将从 2025 年的 6-28% 上升到 2040 年的 7-03%,女性则从 10-82% 上升到 12-18%。预计类风湿性关节炎的年龄标准化发病率男性将从 2025 年的 1-56% 增加到 2040 年的 1-75%,女性将从 2025 年的 2-62% 增加到 2040 年的 2-94%。患有幼年特发性关节炎的儿童和青少年人数预计变化不大(2040 年估计为 8500 人)。根据目前骨关节炎患者每人 2100 澳元、类风湿性关节炎患者每人 1918 澳元的支出水平,保守预测到 2040 年,骨关节炎和类风湿性关节炎的年度医疗系统支出将超过 110-92 亿澳元:这项研究利用最新的国家级数据,对澳大利亚关节炎造成的巨大负担(包括人口规模和医疗成本)进行了现代预测。这些预测强调了资源充足的医疗服务的重要性,这些服务能够为越来越多的关节炎患者提供及时、高价值的医疗服务:资金来源:澳大利亚关节炎协会和国家健康与医学研究委员会。
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来源期刊
Lancet Rheumatology
Lancet Rheumatology RHEUMATOLOGY-
CiteScore
34.70
自引率
3.10%
发文量
279
期刊介绍: The Lancet Rheumatology, an independent journal, is dedicated to publishing content relevant to rheumatology specialists worldwide. It focuses on studies that advance clinical practice, challenge existing norms, and advocate for changes in health policy. The journal covers clinical research, particularly clinical trials, expert reviews, and thought-provoking commentary on the diagnosis, classification, management, and prevention of rheumatic diseases, including arthritis, musculoskeletal disorders, connective tissue diseases, and immune system disorders. Additionally, it publishes high-quality translational studies supported by robust clinical data, prioritizing those that identify potential new therapeutic targets, advance precision medicine efforts, or directly contribute to future clinical trials. With its strong clinical orientation, The Lancet Rheumatology serves as an independent voice for the rheumatology community, advocating strongly for the enhancement of patients' lives affected by rheumatic diseases worldwide.
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