Yi-Jun Pan, Xiao-Lang Jiang, Yan Shan, Peng-Ju Xu, Zhi-Hui Dong, Jiang Lin
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引用次数: 0
Abstract
Objectives: To evaluate the performance of diffusion-weighted imaging (DWI) with an optimal b-value and field-of-view in identifying wall inflammation in abdominal aortic aneurysm (AAA) by comparing it to delayed enhancement T1-weighted imaging (DEI).
Methods: Twenty-five males with AAA were prospectively enrolled and underwent fat-suppressed T1-weighted dark-blood imaging (T1WI), full field-of-view (f-FOV) and reduced field-of-view (r-FOV) DWI (b values = 0, 100, 400 and 800 s/mm2), and DEI. Corresponding images on f-FOV, r-FOV DWI and DEI at the same level were evaluated qualitatively and quantitatively using the paired t-test and Wilcoxon signed-rank test. The agreement in detecting wall inflammation between DWI and DEI sequences was analyzed using weighted kappa statistics.
Results: For both r-FOV and f-FOV DWI, the scores of delineation of aneurysm wall and lesion conspicuity, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were highest on DWI₁₀₀ (Ps < 0.05). The scores of delineation of aneurysm wall, geometric distortion, lesion conspicuity, and SNR, CNR were significantly higher on r-FOV DWI than those on f-FOV DWI (Ps < 0.05). r-FOV DWI₁₀₀ showed comparable performance to DEI in detecting wall inflammation (κ = 0.715), with superior blood suppression and higher SNR and CNR (Ps < 0.05).
Conclusions: DWI with r-FOV and low b-value could be a promising alternative to DEI in identifying wall inflammation in AAA.
期刊介绍:
Magnetic Resonance Imaging (MRI) is the first international multidisciplinary journal encompassing physical, life, and clinical science investigations as they relate to the development and use of magnetic resonance imaging. MRI is dedicated to both basic research, technological innovation and applications, providing a single forum for communication among radiologists, physicists, chemists, biochemists, biologists, engineers, internists, pathologists, physiologists, computer scientists, and mathematicians.