{"title":"The risk of preterm delivery after appendectomy during pregnancy is higher in the face of a negative appendectomy.","authors":"Yoav Baruch, Sabina Razdolsky, Emmanuel Attali, Matan Anteby, Yariv Yogev, Nadav Michaan","doi":"10.1016/j.amjsurg.2024.116120","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Reported outcomes after appendectomy during pregnancy remain inconclusive, and the risk for preterm delivery is not necessarily procedure-related.</p><p><strong>Methods: </strong>This retrospective cohort study included 185 pregnant women who underwent appendectomy during pregnancy and gave birth between 2005 and 2022, compared using a 3:1 ratio to 555 parturients who did not undergo surgery. clinical, obstetrical and neonatal outcomes were analyzed.</p><p><strong>Results: </strong>Laparoscopic appendectomy was the most common procedure (117/185; 63.2 %) whereas 68/185 (36.8 %) had open appendectomy. Pathological findings revealed that 141/185 cases (76.2 %) had an inflamed appendix, while 44/185 (23.8 %) were classified as having a \"white appendix\" (negative appendectomy). Preterm delivery occurred more frequently in the appendectomy group [22/185 (11.9 %) vs 30/555 (5.4 %), p = 0.003] with even higher incidence in negative appendectomies compared to inflamed appendix cases [9/44 (20.5 %) vs 13/141 (9.2 %), p = 0.044]. Multivariate analysis identified appendectomy (but not an inflamed appendix) as the sole significant risk factor for preterm birth (odds ratio 2.3, CI 1.26-4.15, p = 0.006).</p><p><strong>Conclusion: </strong>Preterm delivery correlates with negative appendectomies. Careful assessment is essential to avoid unnecessary surgical interventions during pregnancy.</p>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"116120"},"PeriodicalIF":2.7000,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.amjsurg.2024.116120","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Reported outcomes after appendectomy during pregnancy remain inconclusive, and the risk for preterm delivery is not necessarily procedure-related.
Methods: This retrospective cohort study included 185 pregnant women who underwent appendectomy during pregnancy and gave birth between 2005 and 2022, compared using a 3:1 ratio to 555 parturients who did not undergo surgery. clinical, obstetrical and neonatal outcomes were analyzed.
Results: Laparoscopic appendectomy was the most common procedure (117/185; 63.2 %) whereas 68/185 (36.8 %) had open appendectomy. Pathological findings revealed that 141/185 cases (76.2 %) had an inflamed appendix, while 44/185 (23.8 %) were classified as having a "white appendix" (negative appendectomy). Preterm delivery occurred more frequently in the appendectomy group [22/185 (11.9 %) vs 30/555 (5.4 %), p = 0.003] with even higher incidence in negative appendectomies compared to inflamed appendix cases [9/44 (20.5 %) vs 13/141 (9.2 %), p = 0.044]. Multivariate analysis identified appendectomy (but not an inflamed appendix) as the sole significant risk factor for preterm birth (odds ratio 2.3, CI 1.26-4.15, p = 0.006).
Conclusion: Preterm delivery correlates with negative appendectomies. Careful assessment is essential to avoid unnecessary surgical interventions during pregnancy.
期刊介绍:
The American Journal of Surgery® is a peer-reviewed journal designed for the general surgeon who performs abdominal, cancer, vascular, head and neck, breast, colorectal, and other forms of surgery. AJS is the official journal of 7 major surgical societies* and publishes their official papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews.