5H7c: A rabbit monoclonal antibody detecting ferroptotic cells

Abstract

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Ferroptosis, a cell death pathway triggered by iron-catalyzed peroxidation of phospholipids, has been implicated in both disease progression and cancer treatment.¹ A major challenge in studying ferroptosis has been the difficulty in detecting ferroptotic cells under physiological conditions, owing to the lack of a specific marker for ferroptosis.¹ This obstacle was recently overcome by our study published in Molecular Cell, which identified hyperoxidized PRDX3 as a specific marker for

Declaration of interests

The authors declare no competing interests.