Durable left ventricular assist devices: a contemporary review of their benefits and drawbacks.

Max Shin, Nikhil Ganjoo, Omar Toubat, Rohan Shad, Pavan Atluri
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Abstract

Introduction: Heart transplantation, the gold standard for end-stage cardiomyopathy, is hindered by donor shortages and clinical deterioration. Left ventricular assist devices (LVADs) have emerged as crucial alternatives, stabilizing hemodynamics, reversing end-organ damage, and enabling patient discharge. Significant engineering advancements and iterative improvements have since produced devices capable of rivaling heart transplantation in early survival potential. This review serves to provide an overview of LVAD technology, an understanding of current device limitations, and preview new technologies being developed to address them.

Areas covered: This manuscript reviews the evolution of LVAD technology, discussing its benefits, drawbacks, and contemporary outcomes. It will detail the progression, current state, and future directions of LVAD technology, emphasizing its pivotal role in managing advanced heart failure.

Expert opinion: The modern day LVAD has significantly extended the lifespan of patients with end-stage heart failure. However, adverse events remain abound and will be the focus of the next generation of devices. A burgeoning pipline of new technologies abound and preview the possibilities of a sustainable solution to a devastating disease.

耐用的左心室辅助装置:其优点和缺点的当代回顾。
心脏移植是治疗终末期心肌病的金标准,但由于供体短缺和临床恶化而受到阻碍。左心室辅助装置(lvad)已成为稳定血流动力学,逆转终末器官损伤和使患者出院的关键替代方案。重大的工程进步和反复的改进已经产生了能够在早期生存潜力方面与心脏移植相媲美的设备。这篇综述提供了LVAD技术的概述,了解当前设备的局限性,并预览正在开发的新技术来解决这些问题。涵盖领域:这篇文章回顾了LVAD技术的发展,讨论了它的优点、缺点和当代的结果。它将详细介绍LVAD技术的进展、现状和未来方向,强调其在治疗晚期心力衰竭中的关键作用。专家意见:现代LVAD显著延长了终末期心力衰竭患者的寿命。然而,不良事件仍然很多,这将是下一代设备关注的焦点。新技术层出不穷,预示着一种可持续解决毁灭性疾病的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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