Smartphone-Enabled Point-of-Care Testing for Prehospital Stroke Diagnosis.

IF 2.1 3区医学 Q2 EMERGENCY MEDICINE

Prehospital Emergency Care Pub Date : 2024-12-04 DOI:10.1080/10903127.2024.2437657

Paloma Menéndez-Valladares, Rosa M Delgado, David Núñez-Jurado, Lluis Sempere-Bordes, Anna Penalba, Leire Azurmendi, Claudio Parolo, Ana Barragán, Juan Antonio Cabezas, Carmen de Jesús Gil, José Moreno, Rafael Canto Neguillo, Roberto Valverde de Moyano, José Luis García Garmendia, Mercedes García Murillo, Ismael Muñoz Martínez, Antonia Romero Hidalgo, Francisco Aranda Aguilar, Soledad Pérez Sánchez, Jean-Charles Sánchez, Joan Montaner

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引用次数: 0

Abstract

Objectives: The objective of this study was to evaluate the feasibility of point-of-care testing (POCT) devices for N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurement in prehospital settings, with the aim of improving the speed and accuracy of stroke diagnosis, thereby facilitating quicker and more effective patient care.

Methods: Prehospital blood samples were collected from suspected stroke patients, and NT-proBNP levels were measured using a POCT device in ambulances and hospitals. Results from the NT-proBNP POCT and smartphone images were analyzed. Plasma samples underwent Elecsys® pro BNP II immunoassay after storage at -80 °C.

Results: A total of 121 suspected stroke patients were included in the study. The correlation between POCT measured by the POCT and immunoassay for NT-proBNP was strong (R = 0.926). Smartphone images also strongly correlated with POCT values at 10 minutes (R²=0.9716) and 15 minutes (R²=0.9405). Stability analysis of samples showed consistent NT-proBNP results, and a high correlation (R = 0.907) was observed between plasma and whole blood samples for NT-proBNP POCT.

Conclusions: This study highlights the potential of NT-proBNP POCT devices in ambulances to expedite stroke diagnosis and management within 10 minutes. Smartphone integration further enhances efficiency, adding advancement in prehospital stroke management.

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来源期刊

Prehospital Emergency Care 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.30

自引率

12.50%

发文量

137

审稿时长

1 months

期刊介绍： Prehospital Emergency Care publishes peer-reviewed information relevant to the practice, educational advancement, and investigation of prehospital emergency care, including the following types of articles: Special Contributions - Original Articles - Education and Practice - Preliminary Reports - Case Conferences - Position Papers - Collective Reviews - Editorials - Letters to the Editor - Media Reviews.