Quality and mechanical efficiency of automated knowledge-based planning for volumetric-modulated arc therapy in head and neck cancer.

IF 2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Sangutid Thongsawad, Sasikarn Chamchod, Kornkanok Chawengsaksopak, Wilai Masanga, Aphisara Deeharing, Sarinya Bawornpatarapakorn, Thitiwan Prachanukul, Chirapha Tannanonta, Nuntawat Udee
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引用次数: 0

Abstract

Objectives: This study aimed to examine the effectiveness of the automated RapidPlan in assessing plan quality and to explore how beam complexity affects the mechanical performance of volumetric modulated arc therapy for head and neck cancers.

Materials and methods: The plans were first generated using automated RapidPlan with scripting application programming interface (API) and then further refined through manual optimization (RP+MP) to improve plan quality. The quality of 20 plans was assessed, taking into account dose statistics and clinical plan acceptability. The impact of beam complexity on mechanical performance was analyzed using parameters such as leaf speed (LS), leaf acceleration (LA), mean-field area (MFA), cross-axis score (CAS), closed leaf score (CLS), small aperture score (SAS), and monitor units per control point (MU/CP). Patient-specific quality assurance (PSQA) was conducted to determine differences between the RP+MP and original plans.

Results: No differences in the heterogeneity index and conformity number were observed between the RP+MP and original plans. The RP+MP plan was superior to the original plan for sparing the left cochlea, left and right internal auditory canals, chiasm, and left optic nerve. Significant differences (p < 0.05) were identified in CAS, SAS1 mm, SAS2 mm, and SAS10mm. However, there was no significant difference in PSQA between the RP+MP and original plans. The RP+MP plan without any modifications was clinically acceptable in 45% of cases.

Conclusion: The automated RP with scripting API followed by MP (RP+MP) yielded a high-quality plan in terms of dose statistics and clinical acceptability. The RP+MP plan yielded a higher CAS and SAS compared with the original plan. Nevertheless, there was no significant difference in PSQA between the RP+MP and original plans.

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来源期刊
CiteScore
3.60
自引率
19.00%
发文量
331
审稿时长
3 months
期刊介绍: Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission. JACMP will publish: -Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500. -Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed. -Technical Notes: These should be no longer than 3000 words, including key references. -Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents. -Book Reviews: The editorial office solicits Book Reviews. -Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics. -Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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