DEVELOPING A PRACTICE-DRIVEN TAXONOMY OF IMPLEMENTATION STRATEGIES FOR HIV PREVENTION.

IF 2.9 3区 医学 Q3 IMMUNOLOGY
Sarit A Golub, Carly Wolfer, Alexa Beacham, Benjamin V Lane, Cody A Chastain, Kathrine A Meyers
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Abstract

Background: Effective implementation of evidence-based HIV prevention interventions continues to be a challenge in the United States, and the field is increasingly turning to implementation science for solutions. As such, it is critical to expand the current implementation science vocabulary - and its taxonomy of implementation strategies - to increase its relevance and utility for front-line implementers.

Setting: Community-based health centers providing HIV prevention services in the Southeastern US.

Method: We conducted a collective case-study analysis, combining document review and qualitative interviews with program directors, clinicians, and other providers (N = 30) at five sites. We employed an inductive and iterative analytic approach to specify and categorize strategies, and then conducted in-depth cross-case analysis to derive a practice-driven taxonomy of HIV prevention implementation strategies.

Results: From an initial matrix of 264 activities, we identified 50 strategies common across sites. In contrast to existing implementation science frameworks, the majority (68%, n = 34) of strategies were designed to impact implementation outcomes (e.g., acceptability, adoption, feasibility) for patients. We present a practice-driven taxonomy of these strategies, operationalized according to implementation science literature, but with terminology that more directly relates to implementers.

Conclusions: Findings demonstrate the feasibility and utility of this method for developing a practice-driven implementation science vocabulary for HIV prevention. Our evidence-based taxonomy provides a framework for implementers seeking data about the universe of strategies they might consider for their own programs, and increases researchers' ability to measure and evaluate the effectiveness of implementation strategies being enacted in practice settings.

制定以实践为导向的艾滋病毒预防实施战略分类学。
背景:有效实施基于证据的艾滋病预防干预措施在美国仍然是一个挑战,该领域越来越多地转向实施科学寻求解决方案。因此,扩展当前的实现科学词汇表——及其实现策略的分类——以增加其对一线实现者的相关性和实用性是至关重要的。环境:在美国东南部提供艾滋病预防服务的社区卫生中心。方法:我们进行了集体案例研究分析,结合文献回顾和与五个地点的项目主任、临床医生和其他提供者(N = 30)的定性访谈。我们采用归纳和迭代分析的方法对策略进行具体和分类,然后进行深入的跨案例分析,得出一个实践驱动的艾滋病预防实施策略分类。结果:从264个活动的初始矩阵中,我们确定了50个跨站点的共同策略。与现有的实施科学框架相比,大多数(68%,n = 34)的策略旨在影响患者的实施结果(例如,可接受性、采用性、可行性)。我们提出了这些策略的实践驱动分类法,根据实施科学文献进行操作,但使用与实现者更直接相关的术语。结论:研究结果证明了该方法在开发艾滋病毒预防实践驱动的实施科学词汇方面的可行性和实用性。我们的基于证据的分类法为实施者提供了一个框架,他们可以在自己的项目中寻找有关策略范围的数据,并提高了研究人员在实践环境中衡量和评估实施策略有效性的能力。
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来源期刊
CiteScore
5.80
自引率
5.60%
发文量
490
审稿时长
3-6 weeks
期刊介绍: JAIDS: Journal of Acquired Immune Deficiency Syndromes​ seeks to end the HIV epidemic by presenting important new science across all disciplines that advance our understanding of the biology, treatment and prevention of HIV infection worldwide. JAIDS: Journal of Acquired Immune Deficiency Syndromes is the trusted, interdisciplinary resource for HIV- and AIDS-related information with a strong focus on basic and translational science, clinical science, and epidemiology and prevention. Co-edited by the foremost leaders in clinical virology, molecular biology, and epidemiology, JAIDS publishes vital information on the advances in diagnosis and treatment of HIV infections, as well as the latest research in the development of therapeutics and vaccine approaches. This ground-breaking journal brings together rigorously peer-reviewed articles, reviews of current research, results of clinical trials, and epidemiologic reports from around the world.
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