Feasibility of Using Continuous Glucose Monitoring to Detect Glycemic Abnormalities in Children with Cystic Fibrosis.

IF 2.6 3区 医学 Q3 ENDOCRINOLOGY & METABOLISM
Amanda Leonard, Isabel R Judware, Lori L Vanscoy, Shruti M Paranjape, Donna Peeler, Malinda Wu, Scott M Blackman, Peter J Mogayzel
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Abstract

Introduction: Cystic fibrosis-related diabetes (CFRD) is linked to worsening pulmonary function and increased mortality in people with cystic fibrosis (CF). Because of this correlation, early recognition of CFRD is important. Current recommendations for detecting glucose abnormalities using an oral glucose tolerance test (OGTT) can be difficult to achieve in a busy clinical setting.

Methods: We trialed a 10-day continuous glucose monitoring (CGM) (Dexcom G6Pro) session in patients seen in our pediatric CF clinic that could not do an OGTT (reasons include emesis with OGTT or fear of needles) or that had an abnormal OGTT (to gather additional data to make treatment decisions).

Results: Of the 36 sensors placed, 34 (94%) were returned. Devices were worn for a median of 10 days (range 4-10 days). Of the 34 CGMs returned, 20 (59%) met the criterion for referral to a pediatric endocrinologist.

Conclusion: CGM placement is feasible in a busy CF clinic to detect glucose abnormalities in children.

使用连续葡萄糖监测仪检测囊性纤维化患儿血糖异常的可行性。
导言:囊性纤维化相关糖尿病(CFRD)与囊性纤维化患者(pwCF)肺功能恶化和死亡率增加有关。由于这种相关性,早期识别囊性纤维化相关糖尿病非常重要。目前使用口服葡萄糖耐量试验(OGTT)检测血糖异常的建议在繁忙的临床环境中很难实现:方法:我们在儿科 CF 诊所对无法进行 OGTT(原因包括 OGTT 引起的呕吐或对针头的恐惧)或 OGTT 异常的患者试用了为期 10 天的 CGM(Dexcom G6Pro):在放置的 36 个传感器中,34 个(94%)被退回。设备佩戴时间的中位数为 10 天(4-10 天不等)。在退回的 34 个 CGM 中,20 个(59%)符合转诊至儿科内分泌专家的标准:结论:在繁忙的 CF 诊所安装 CGM 检测儿童血糖异常是可行的。
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来源期刊
Hormone Research in Paediatrics
Hormone Research in Paediatrics ENDOCRINOLOGY & METABOLISM-PEDIATRICS
CiteScore
4.90
自引率
6.20%
发文量
88
审稿时长
4-8 weeks
期刊介绍: The mission of ''Hormone Research in Paediatrics'' is to improve the care of children with endocrine disorders by promoting basic and clinical knowledge. The journal facilitates the dissemination of information through original papers, mini reviews, clinical guidelines and papers on novel insights from clinical practice. Periodic editorials from outstanding paediatric endocrinologists address the main published novelties by critically reviewing the major strengths and weaknesses of the studies.
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