Neonatal conjunctivitis at a Brazilian tertiary center: the current relevance of Chlamydia trachomatis.

IF 1.1 4区 医学 Q3 OPHTHALMOLOGY
Arquivos brasileiros de oftalmologia Pub Date : 2024-11-22 eCollection Date: 2024-01-01 DOI:10.5935/0004-2749.2023-0290
Juliana Mika Kato, Eduardo Ferracioli Oda, Thaisa Silveira Barbosa, Flavia Rossi, Andre Mario Doi, Carolina Dos Santos Lazari, Tatiana Tanaka, Joyce Hisae Yamamoto
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引用次数: 0

Abstract

Purpose: The microbiology pattern of neonatal conjunctivitis has changed over time, and the incidence of gonococcal conjunctivitis is almost nil. This study aimed to determine the etiology of neonatal conjunctivitis cases referred to a tertiary health center in Brazil.

Methods: From 2017 to 2020, conjunctival swabs were taken from neonates with clinical signs of conjunctivitis and tested with bacterial culture and polymerase chain reaction for Neisseria gonorrhoeae and Chlamydia trachomatis.

Results: A total of 51 neonates were included in the 3-year study. Chlamydial conjunctivitis was diagnosed in 39 (76.5%) patients, and microbial growth was detected in 13 (25.5%) patients. The most isolated bacterium was Staphylococcus epidermidis (n=6, 11.8%), followed by other coagulase-negative Staphylococcus species (n=4, 7.8%) and S. aureus (n=2, 3.9%). One S. aureus isolate was resistant to oxacillin. There were no cases of gonococcal conjunctivitis. Ten (19.6%) patients showed polymerase chain reaction-negative C. trachomatis and negative bacterial culture test results.

Conclusion: Findings show that C. trachomatis is the most common pathogen causing neonatal conjunctivitis. The high prevalence of C. trachomatis infection highlights the importance of screening and treating pregnant woman.

巴西一家三级医疗中心的新生儿结膜炎:沙眼衣原体的现实意义。
目的:随着时间的推移,新生儿结膜炎的微生物学模式发生了变化,淋球菌性结膜炎的发病率几乎为零。本研究旨在确定转诊至巴西一家三级医疗中心的新生儿结膜炎病例的病因:从 2017 年到 2020 年,从有结膜炎临床症状的新生儿身上采集结膜拭子,用细菌培养和聚合酶链反应对淋病奈瑟菌和沙眼衣原体进行检测:这项为期 3 年的研究共纳入 51 名新生儿。39名(76.5%)患者被诊断为衣原体结膜炎,13名(25.5%)患者被检测到微生物生长。分离最多的细菌是表皮葡萄球菌(6 个,占 11.8%),其次是其他凝固酶阴性葡萄球菌(4 个,占 7.8%)和金黄色葡萄球菌(2 个,占 3.9%)。有一个分离出的金黄色葡萄球菌对奥沙西林耐药。没有淋球菌性结膜炎病例。10例(19.6%)患者的沙眼衣原体聚合酶链反应阴性,细菌培养检测结果阴性:研究结果表明,沙眼衣原体是导致新生儿结膜炎的最常见病原体。沙眼衣原体感染的高流行率凸显了筛查和治疗孕妇的重要性。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
200
审稿时长
6-12 weeks
期刊介绍: The ABO-ARQUIVOS BRASILEIROS DE OFTALMOLOGIA (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - electronic version), the official bimonthly publication of the Brazilian Council of Ophthalmology (CBO), aims to disseminate scientific studies in Ophthalmology, Visual Science and Health public, by promoting research, improvement and updating of professionals related to the field.
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