An analytical study of micro-droplet generation in microfluidic double T-junction devices under effects of channel depth ratio using VOF method

IF 2.2 3区 工程技术 Q2 MECHANICS
Minh Duc Nguyen, The Khanh Lai, Ich Long Ngo
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引用次数: 0

Abstract

This paper describes a numerical study on micro-droplet generation in a microfluidic double T-junction device under the effects of channel depth using the Volume-Of-Fluid method. The effects of various parameters such as capillary number (Ca), water fraction (wf), viscosity ratio \((\beta )\), and particularly the channel depth ratio \((\varepsilon )\) were examined. Consequently, the numerical results match well with the experimental data obtained in the literature. Additionally, the micro-droplet size increases with increasing the channel depth ratio. A phase diagram with four main micro-droplet generation regimes is provided. Particularly, the alternating mode is narrowed in both Ca and wf ranges when increasing \(\varepsilon \). Moreover, four regimes of micro-droplet generation with the presence of channel depth were first discovered in the present study, and the stable micro-droplet generation regime can be gained within an effective range of both \(\varepsilon \) and \(\beta \). These results are very useful and valuable for many applications in emulsion production, hydrogel particle generation, and drug delivery synthesis in biomedical treatment.

使用 VOF 方法分析研究通道深度比影响下微流体双 T 型连接装置中微液滴的生成情况
本文采用流体容积法(Volume-Of-Fluid method)对微流体双 T 型连接装置中通道深度影响下的微液滴生成进行了数值研究。研究了各种参数的影响,如毛细管数(Ca)、水分量(wf)、粘度比((\beta)\),特别是通道深度比((\varepsilon)\)。因此,数值结果与文献中获得的实验数据非常吻合。此外,微滴尺寸随着通道深度比的增加而增大。研究提供了四种主要微滴生成模式的相图。特别是当\(\varepsilon \)增大时,交替模式在 Ca 和 wf 范围内都变窄了。此外,本研究首次发现了存在通道深度的四种微液滴生成机制,并且在有效的(\varepsilon \)和(\beta \)范围内都能获得稳定的微液滴生成机制。这些结果对于乳液生产、水凝胶颗粒生成和生物医学治疗中的药物输送合成等方面的许多应用都是非常有用和有价值的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.80
自引率
2.90%
发文量
38
审稿时长
>12 weeks
期刊介绍: Theoretical and Computational Fluid Dynamics provides a forum for the cross fertilization of ideas, tools and techniques across all disciplines in which fluid flow plays a role. The focus is on aspects of fluid dynamics where theory and computation are used to provide insights and data upon which solid physical understanding is revealed. We seek research papers, invited review articles, brief communications, letters and comments addressing flow phenomena of relevance to aeronautical, geophysical, environmental, material, mechanical and life sciences. Papers of a purely algorithmic, experimental or engineering application nature, and papers without significant new physical insights, are outside the scope of this journal. For computational work, authors are responsible for ensuring that any artifacts of discretization and/or implementation are sufficiently controlled such that the numerical results unambiguously support the conclusions drawn. Where appropriate, and to the extent possible, such papers should either include or reference supporting documentation in the form of verification and validation studies.
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