A Mendelian randomization study finds no evidence for causal effects of C-reactive protein (CRP) on chronic pain conditions.

IF 2.9 3区医学 Q1 ANESTHESIOLOGY

Pain Medicine Pub Date : 2024-11-26 DOI:10.1093/pm/pnae122

Pradeep Suri, Yakov A Tsepilov, Elizaveta E Elgaeva, Frances M K Williams, Maxim B Freidin, Ian B Stanaway

引用次数: 0

Abstract

This two-sample Mendelian randomization study examined causal associations of C-reactive protein (CRP) with spinal pain, the extent of multisite chronic pain, and chronic widespread musculoskeletal pain. No causal associations were found between CRP and these pain conditions.

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一项孟德尔随机研究发现，没有证据表明 C 反应蛋白 (CRP) 对慢性疼痛有因果影响。

这项双样本孟德尔随机研究考察了C反应蛋白（CRP）与脊柱疼痛、多部位慢性疼痛程度以及慢性广泛性肌肉骨骼疼痛之间的因果关系。结果发现，CRP 与这些疼痛状况之间没有因果关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pain Medicine 医学-医学：内科

CiteScore

6.50

自引率

3.20%

发文量

187

审稿时长

3 months

期刊介绍： Pain Medicine is a multi-disciplinary journal dedicated to pain clinicians, educators and researchers with an interest in pain from various medical specialties such as pain medicine, anaesthesiology, family practice, internal medicine, neurology, neurological surgery, orthopaedic spine surgery, psychiatry, and rehabilitation medicine as well as related health disciplines such as psychology, neuroscience, nursing, nurse practitioner, physical therapy, and integrative health.