Kate Rich, Liezel Engelbrecht, Gabrielle Wills, Edzani Mphaphuli
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引用次数: 0
Abstract
A large body of research investigates the determinants of stunting in young children, but few studies have considered which factors are the most important predictors of stunting. We examined the relative importance of predictors of height-for-age z-scores (HAZ) and stunting among children under 5 years of age in seven of the most food-insecure districts in South Africa using data from the Grow Great Community Stunting Survey of 2022. We used dominance analysis and variable importance measures from conditional random forest models to assess the relative importance of predictors. We found that intergenerational and socioeconomic factors-specifically maternal height (HAZ: Coef. 0.02, 95% CI 0.01-0.03; stunting: OR 0.96, 95% CI 0.94-0.98), birth weight (HAZ: Coef. 0.3, 95% CI 0.16-0.43; stunting: OR 0.5, 95% CI 0.35-0.72) and asset-based measures of socioeconomic status (HAZ: Coef. 0.17, 95% CI 0.10-0.24; stunting: OR 0.77, 95% CI 0.67-0.89)-were the most important predictors of HAZ and stunting in these districts. We explored whether any other factors moderated (weakened) the relationship between these intergenerational factors and child height using conditional inference trees and moderation analysis. We found that being on track for vitamin A and deworming, adequate sanitation, a diverse diet and good maternal mental health moderated the effect of birth weight or mother's height. Though impacts are likely to be small relative to the impact of intergenerational risk factors, these moderating factors may provide promising avenues for helping to mitigate the intergenerational transmission of stunting risk in South Africa.
大量研究调查了幼儿发育迟缓的决定因素,但很少有研究考虑哪些因素是预测发育迟缓的最重要因素。我们利用 2022 年 "社区发育迟缓大调查"(Grow Great Community Stunting Survey)的数据,研究了南非七个粮食最不安全地区 5 岁以下儿童身高-年龄 z 值(HAZ)和发育迟缓预测因素的相对重要性。我们使用条件随机森林模型中的优势分析和变量重要性度量来评估预测因子的相对重要性。我们发现,代际因素和社会经济因素--特别是母亲身高(HAZ:Coef.0.02,95% CI 0.01-0.03;发育迟缓:OR 0.96,95% CI 0.94-0.98)、出生体重(HAZ:Coef.0.3,95% CI 0.16-0.43;发育迟缓:OR 0.5,95% CI 0.35-0.72)和基于资产的社会经济地位测量(HAZ:Coef. 0.17,95% CI 0.10-0.24;发育迟缓:OR 0.77,95% CI 0.67-0.89)--是这些地区 HAZ 和发育迟缓最重要的预测因素。我们利用条件推理树和调节分析探讨了是否有其他因素调节(削弱)了这些代际因素与儿童身高之间的关系。我们发现,按时服用维生素 A 和驱虫药、充足的卫生条件、多样化的饮食以及良好的孕产妇心理健康都会调节出生体重或母亲身高的影响。虽然相对于代际风险因素的影响而言,这些影响可能较小,但这些调节因素可能为帮助减轻南非发育迟缓风险的代际传播提供了有希望的途径。
期刊介绍:
Maternal & Child Nutrition addresses fundamental aspects of nutrition and its outcomes in women and their children, both in early and later life, and keeps its audience fully informed about new initiatives, the latest research findings and innovative ways of responding to changes in public attitudes and policy. Drawing from global sources, the Journal provides an invaluable source of up to date information for health professionals, academics and service users with interests in maternal and child nutrition. Its scope includes pre-conception, antenatal and postnatal maternal nutrition, women''s nutrition throughout their reproductive years, and fetal, neonatal, infant, child and adolescent nutrition and their effects throughout life.