On the impact of improved dose calculation accuracy in clinical treatment planning for superficial high-dose-rate brachytherapy of extensive scalp lesions

IF 3.4 Q2 ONCOLOGY
Giulio Rossi , Vasiliki Peppa , Mark Gainey , Michael Kollefrath , Tanja Sprave , Panagiotis Papagiannis , Dimos Baltas
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引用次数: 0

Abstract

TG-43-based dose calculations disregard tissue heterogeneities and finite scatter conditions, prompting the introduction of model-based dose calculation algorithms (MBDCAs) to improve accuracy in high-dose-rate (HDR) brachytherapy. This study evaluated the effectiveness of MBDCAs over TG-43 in HDR 192Ir brachytherapy of extended scalp lesions. Treatment planning dose calculations were compared with Monte Carlo (MC) data. TG-43 exhibited a dose overestimation ranging from 10% to 23% as the distance from the implant increased, while a better agreement from 2% to 6% was observed between the MBDCA and MC, supporting the adoption of MBDCAs for dose calculations in broad scalp lesions.
提高剂量计算精度对广泛头皮病变浅表高剂量率近距离放射治疗临床治疗规划的影响
基于 TG-43 的剂量计算忽略了组织异质性和有限散射条件,这促使人们引入基于模型的剂量计算算法 (MBDCAs),以提高高剂量率近距离放射治疗的准确性。本研究评估了 MBDCAs 与 TG-43 相比在 HDR 192Ir 近距离治疗扩展头皮病变中的有效性。将治疗计划剂量计算与蒙特卡罗(MC)数据进行了比较。随着与植入物距离的增加,TG-43 显示出 10% 到 23% 的剂量高估,而 MBDCA 和 MC 之间的一致性较好,从 2% 到 6%,支持采用 MBDCAs 对头皮广泛病变进行剂量计算。
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来源期刊
Physics and Imaging in Radiation Oncology
Physics and Imaging in Radiation Oncology Physics and Astronomy-Radiation
CiteScore
5.30
自引率
18.90%
发文量
93
审稿时长
6 weeks
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