Congenital teratoma of the oral cavity - the largest personal series of cases.

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-22 DOI:10.1007/s10006-024-01307-1

Renato da Silva Freitas, Bruna Ferreira Bernert, Isis Juliane Guarezi Nasser, Fabiola Grigoletto Lupion, Eduardo Angeli-Freitas, Cesar Vinícius Grande

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引用次数: 0

Abstract

Purpose: The objective of this study is to present the largest personal series of oral teratomas already published in English literature and discuss the diagnosis, neonatal management, and surgical treatment of this disorder.

Method: The study included patients treated by the senior author (RSF) between 2004 and 2023. Data were collected regarding prenatal evaluation, perinatal approach, surgical management, evolution, and treatment of secondary deformities. In addition, we performed a literature review on the topic.

Results: Twelve patients with oral teratoma were included in this study. Seven cases did not have been submitted to any previous treatment, and five cases had already undergone some treatment in another institution. Four cases were diagnosed as epignathus (33.3%), two as true teratomas (16.6%), four as teratoid teratomas (33.3%), one as dermoid teratoma (8.3%) and one as fetus in fetus (8.3%). All patients, except for one, had the tumor surgically removed with good evolution. There was one case of recurrence, successfully operated. The most frequently associated comorbidity was 0-14 fissure, present in 66% of the cases.

Conclusion: The experience of our twelve cases indicates that prenatal diagnosis, associated with good multidisciplinary planning of the delivery care, and complete resection of the masses reveal high success rates in the treatment of this pathology.

Clinical trial number: This study was performed in line with the principles of the declaration of Helsinki. Approval was granted by the Ethics Committee of Federal University of Paraná - 47102421.2.0000.5225.

查看原文本刊更多论文

口腔先天性畸胎瘤--最大的个人病例系列。

目的：本研究旨在介绍已发表在英文文献中的最大规模的口腔畸胎瘤个人系列，并讨论该疾病的诊断、新生儿管理和手术治疗：研究对象包括资深作者（RSF）在 2004 年至 2023 年间治疗的患者。研究收集了有关产前评估、围产期方法、手术治疗、演变和继发性畸形治疗的数据。此外，我们还查阅了相关文献：本研究共纳入 12 例口腔畸胎瘤患者。结果：本研究共纳入 12 例口腔畸胎瘤患者，其中 7 例之前未接受过任何治疗，5 例已在其他机构接受过治疗。其中四例被诊断为附壁瘤（33.3%），两例为真畸胎瘤（16.6%），四例为畸胎瘤（33.3%），一例为皮样畸胎瘤（8.3%），一例为胎中胎（8.3%）。除一名患者外，所有患者均通过手术切除了肿瘤，病情发展良好。有一例复发病例，手术成功。最常见的合并症是 0-14 裂隙，占病例总数的 66%：我们 12 例病例的经验表明，产前诊断、良好的多学科分娩护理计划和肿块的完全切除在治疗这种病变方面具有很高的成功率：本研究按照赫尔辛基宣言的原则进行。巴拉那联邦大学伦理委员会（Ethics Committee of Federal University of Paraná - 47102421.2.0000.5225）批准了这项研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral and Maxillofacial Surgery-Heidelberg DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.20

自引率

5.60%

发文量

118

期刊介绍： Oral & Maxillofacial Surgery founded as Mund-, Kiefer- und Gesichtschirurgie is a peer-reviewed online journal. It is designed for clinicians as well as researchers.The quarterly journal offers comprehensive coverage of new techniques, important developments and innovative ideas in oral and maxillofacial surgery and interdisciplinary aspects of cranial, facial and oral diseases and their management. The journal publishes papers of the highest scientific merit and widest possible scope on work in oral and maxillofacial surgery as well as supporting specialties. Practice-oriented articles help improve the methods used in oral and maxillofacial surgery.Every aspect of oral and maxillofacial surgery is fully covered through a range of invited review articles, clinical and research articles, technical notes, abstracts, and case reports. Specific topics are: aesthetic facial surgery, clinical pathology, computer-assisted surgery, congenital and craniofacial deformities, dentoalveolar surgery, head and neck oncology, implant dentistry, oral medicine, orthognathic surgery, reconstructive surgery, skull base surgery, TMJ and trauma.Time-limited reviewing and electronic processing allow to publish articles as fast as possible. Accepted articles are rapidly accessible online.Clinical studies submitted for publication have to include a declaration that they have been approved by an ethical committee according to the World Medical Association Declaration of Helsinki 1964 (last amendment during the 52nd World Medical Association General Assembly, Edinburgh, Scotland, October 2000). Experimental animal studies have to be carried out according to the principles of laboratory animal care (NIH publication No 86-23, revised 1985).