Changes in Segmental and Lumbar Lordosis Following Lumbar Interbody Fusion: A Systematic Review and Meta-Analysis.

IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY
Elizabeth A Lechtholz-Zey, Mina Ayad, Brandon S Gettleman, Emily S Mills, Hannah Shelby, Andy Ton, William J Karakash, Ishan Shah, Jeffrey C Wang, Ram K Alluri, Raymond J Hah
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引用次数: 0

Abstract

Study design: Systematic review and meta-analysis.

Objective: To compare radiographic outcomes across lumbar interbody fusion (LIF) techniques, assessing segmental and global lumbar lordosis restoration.

Summary of background data: LIF is a commonly utilized procedure to treat various spinal conditions, including degenerative pathology and adult spinal deformity. Common approaches include posterior LIF (PLIF), transforaminal LIF (TLIF), anterior LIF (ALIF), oblique LIF (OLIF), and lateral LIF (LLIF).

Methods: A systematic review and meta-analysis were carried out using PRISMA guidelines with appropriate MeSH terms. Papers were included based on relevance, number of patients, and a minimum of 1-year radiographic follow-up. Radiographic outcomes included segmental lordosis (SL) and lumbar lordosis (LL). Only papers directly comparing SL restoration between two or more LIF techniques were utilized in the systematic review, while all articles meeting the aforementioned criteria were used in the meta-analysis.

Results: Nineteen studies were included in the final systematic review, and 88 papers were included in the meta-analysis. Seven studies in the systematic review showed a significantly higher increase in SL with ALIF versus TLIF, and two showed significantly higher SL gain with ALIF compared with LLIF. When comparing ALIF versus OLIF, one study favored ALIF, while another favored OLIF for SL restoration. OLIF likewise demonstrated superior restoration of SL compared with TLIF. LLIF demonstrated improved SL restoration compared with TLIF in 2 of the 3 studies comparing the 2 procedures. Furthermore, both ALIF and OLIF demonstrated superior LL restoration compared with TLIF in 4 and 3 studies, respectively. The meta-analysis results demonstrated that ALIF provided significantly better restoration of SL than TLIF, LLIF, and OLIF, while TLIF conferred significantly lower SL restoration than ALIF and OLIF. Similarly, LL restoration was significantly reduced with TLIF relative to OLIF and LLIF (all P<0.05).

Conclusions: The included studies demonstrated superior SL and LL restoration with ALIF, OLIF, and LLIF compared with TLIF. ALIF improved SL to a greater extent when directly compared with all other interbody techniques.

腰椎椎间融合术后节段和腰椎后凸的变化:系统回顾与元分析》。
研究设计系统回顾和荟萃分析:比较各种腰椎椎间融合术(LIF)的影像学结果,评估节段性和整体性腰椎前凸恢复情况:腰椎椎间融合术是治疗各种脊柱疾病的常用手术,包括退行性病变和成人脊柱畸形。常用的方法包括后路 LIF (PLIF)、经椎孔 LIF (TLIF)、前路 LIF (ALIF)、斜向 LIF (OLIF) 和侧向 LIF (LLIF):采用 PRISMA 指南和适当的 MeSH 术语进行了系统综述和荟萃分析。根据相关性、患者人数和至少 1 年的放射学随访纳入论文。放射学结果包括节段前凸(SL)和腰椎前凸(LL)。只有直接比较两种或两种以上 LIF 技术的 SL 恢复情况的论文才会被用于系统综述,而所有符合上述标准的文章都会被用于荟萃分析:最终有 19 项研究被纳入系统综述,88 篇论文被纳入荟萃分析。系统综述中有 7 项研究显示,ALIF 与 TLIF 相比,SL 的增加幅度明显更高;有 2 项研究显示,ALIF 与 LLIF 相比,SL 的增加幅度明显更高。在比较 ALIF 和 OLIF 时,一项研究倾向于 ALIF,而另一项研究则倾向于 OLIF 的 SL 恢复。与 TLIF 相比,OLIF 同样显示出更佳的 SL 恢复效果。在比较两种手术的 3 项研究中,有 2 项研究表明 LLIF 比 TLIF 更能恢复 SL。此外,分别在 4 项和 3 项研究中,ALIF 和 OLIF 的 LL 恢复均优于 TLIF。荟萃分析结果表明,ALIF 的 SL 恢复明显优于 TLIF、LLIF 和 OLIF,而 TLIF 的 SL 恢复明显低于 ALIF 和 OLIF。同样,与 OLIF 和 LLIF 相比,TLIF 的 LL 恢复能力明显降低(所有 PConclusions):纳入的研究表明,与TLIF相比,ALIF、OLIF和LLIF的SL和LL恢复能力更强。与所有其他椎间孔镜技术直接比较,ALIF 对 SL 的改善程度更大。
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来源期刊
Clinical Spine Surgery
Clinical Spine Surgery Medicine-Surgery
CiteScore
3.00
自引率
5.30%
发文量
236
期刊介绍: Clinical Spine Surgery is the ideal journal for the busy practicing spine surgeon or trainee, as it is the only journal necessary to keep up to date with new clinical research and surgical techniques. Readers get to watch leaders in the field debate controversial topics in a new controversies section, and gain access to evidence-based reviews of important pathologies in the systematic reviews section. The journal features a surgical technique complete with a video, and a tips and tricks section that allows surgeons to review the important steps prior to a complex procedure. Clinical Spine Surgery provides readers with primary research studies, specifically level 1, 2 and 3 studies, ensuring that articles that may actually change a surgeon’s practice will be read and published. Each issue includes a brief article that will help a surgeon better understand the business of healthcare, as well as an article that will help a surgeon understand how to interpret increasingly complex research methodology. Clinical Spine Surgery is your single source for up-to-date, evidence-based recommendations for spine care.
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