Health impacts of takeaway management zones around schools in six different local authorities across England: a public health modelling study using PRIMEtime.

IF 7 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Nina Trivedy Rogers, Ben Amies-Cull, Jean Adams, Michael Chang, Steven Cummins, Daniel Derbyshire, Suzan Hassan, Matthew Keeble, Bochu Liu, Antonieta Medina-Lara, Bea Savory, John Rahilly, Richard Smith, Claire Thompson, Martin White, Oliver Mytton, Thomas Burgoine
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引用次数: 0

Abstract

Background: In England, the number of takeaway food outlets ('takeaways') has been increasing for over two decades. Takeaway management zones around schools are an effective way to restrict the growth of new takeaways but their impacts on population health have not been estimated.

Methods: To model the impact of takeaway management zones on health, we used estimates of change in and exposure to takeaways (across home, work, and commuting buffers) based on a previous evaluation suggesting that 50% of new outlets were prevented from opening because of management zones. Based on previous cross-sectional findings, we estimated changes in body mass index (BMI) from changes in takeaway exposure, from 2018 to 2040. We used PRIMEtime, a proportional multistate lifetable model, and BMI change to estimate the impact of the intervention, in a closed-cohort of adults (25-64 years), on incidence of 12 non-communicable diseases, obesity prevalence, quality-adjusted life years (QALYs), and healthcare costs saved by 2040 in six local authorities (LAs) across the rural-urban spectrum in England (Wandsworth, Manchester, Blackburn with Darwen, Sheffield, North Somerset, and Fenland).

Results: By 2031, compared to no intervention, reductions in outlet exposure ranged from 3 outlets/person in Fenland to 28 outlets/person in Manchester. This corresponded to mean per person reductions in BMI of 0.08 and 0.68 kg/m2, respectively. Relative to no intervention, obesity prevalence was estimated to be reduced in both sexes in all LAs, including by 2.3 percentage points (PP) (95% uncertainty interval:2.9PP, 1.7PP) to 1.5PP (95%UI:1.9PP, 1.1PP) in males living in Manchester and Wandsworth by 2040, respectively. Model estimates showed reductions in incidence of disease, including type II diabetes (e.g. 964 (95% UI: 1565, 870) fewer cases/100,000 population for males in Manchester)), cardiovascular diseases, asthma, certain cancers, and low back pain. Savings in healthcare costs (millions) ranged from £1.65 (95% UI: £1.17, £2.25)/100,000 population in North Somerset to £2.02 (95% UI: £1.39, £2.83)/100,000 population in Wandsworth. Gains in QALYs/100,000 person were broadly similar across LAs.

Conclusions: Takeaway management zones in England have the potential to meaningfully contribute towards reducing obesity prevalence and associated healthcare burden in the adult population, at the local level and across the rural-urban spectrum.

英格兰六个不同地方当局的学校周边外卖管理区对健康的影响:利用 PRIMEtime 进行的公共卫生建模研究。
背景:在英格兰,外卖食品店("外卖")的数量二十多年来一直在增加。学校周围的外卖管理区是限制新外卖增长的有效方法,但其对人口健康的影响尚未得到估算:为了模拟外卖管理区对健康的影响,我们使用了外卖变化和暴露于外卖的估计值(跨越家庭、工作和通勤缓冲区),该估计值基于之前的一项评估,该评估表明,由于外卖管理区的存在,50% 的新外卖店被阻止开张。根据之前的横截面研究结果,我们估算了从 2018 年到 2040 年,外卖暴露量的变化所带来的体重指数(BMI)变化。我们使用 PRIMEtime(一种比例多态生命表模型)和 BMI 变化来估算干预措施对 12 种非传染性疾病发病率、肥胖症发病率、质量调整生命年(QALYs)的影响,以及到 2040 年在英格兰城乡结合部六个地方当局(LAs)(旺兹沃斯、曼彻斯特、布莱克本与达文、谢菲尔德、北萨默塞特和芬兰)节约的医疗成本:到 2031 年,与不采取任何干预措施相比,芬兰的销售点暴露量减少了 3 个/人,曼彻斯特的销售点暴露量减少了 28 个/人。这相当于平均每人的体重指数分别降低了 0.08 和 0.68 公斤/平方米。与不采取干预措施相比,估计所有洛杉矶地区的男女肥胖症发病率都会降低,其中居住在曼彻斯特和旺兹沃思的男性肥胖症发病率到 2040 年将分别降低 2.3 个百分点(95% 不确定区间:2.9 个百分点,1.7 个百分点)至 1.5 个百分点(95% 不确定区间:1.9 个百分点,1.1 个百分点)。模型估算结果显示,疾病发病率有所降低,包括 II 型糖尿病(例如,曼彻斯特的男性病例数/100,000 人减少了 964 例(95% UI:1565,870))、心血管疾病、哮喘、某些癌症和腰背痛。节省的医疗成本(百万)从北萨默塞特的 1.65 英镑(95% 置信区间:1.17 英镑,2.25 英镑)/100,000 人到旺兹沃思的 2.02 英镑(95% 置信区间:1.39 英镑,2.83 英镑)/100,000 人不等。各地方行政区的 QALYs 收益/100,000 人大致相似:结论:英格兰的外卖管理区有可能在地方层面和城乡范围内有效降低成年人的肥胖患病率和相关医疗负担。
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来源期刊
BMC Medicine
BMC Medicine 医学-医学:内科
CiteScore
13.10
自引率
1.10%
发文量
435
审稿时长
4-8 weeks
期刊介绍: BMC Medicine is an open access, transparent peer-reviewed general medical journal. It is the flagship journal of the BMC series and publishes outstanding and influential research in various areas including clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. In addition to research articles, the journal also publishes stimulating debates, reviews, unique forum articles, and concise tutorials. All articles published in BMC Medicine are included in various databases such as Biological Abstracts, BIOSIS, CAS, Citebase, Current contents, DOAJ, Embase, MEDLINE, PubMed, Science Citation Index Expanded, OAIster, SCImago, Scopus, SOCOLAR, and Zetoc.
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