Malignant Soft Tissue Deposits in Advanced Cancer Larynx, a Prospective Study.

IF 0.6 Q4 SURGERY

Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2024-12-01 Epub Date: 2024-09-19 DOI:10.1007/s12070-024-05021-y

Ahmad Mohamed Eltelety, Amir Zaki, Hazem Dewidar, Shady Elia Anis, Ahmed El Batawi, Ahmed Amin Nassar

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引用次数: 0

Abstract

The purpose of this study was to evaluate the incidence and predictors of malignant soft tissue deposits (MSTDs) in advanced laryngeal carcinoma. MSTDs prognostic value on locoregional recurrence within 2 years after curative surgery was also studied. 40 patients with cT3/cT4 N0 laryngeal squamous cell carcinoma (SCC) were prospectively involved in the study. Soft tissue specimens were histopathologically examined for MSTDs. MSTDs were observed in 4 patients. Six patients had extranodal extension (ENE), four of whom showed MSTDs. All patients with MSTDs had associated comorbidities. cTNM staging, preoperative tracheostomy, tumor grade and surgical margins were not related to the incidence of MSTDs. The incidence of MSTDs in our report was less than that previously reported in the literature. MSTDs did not influence locoregional recurrence and did not influence the overall outcome. MSTDs were less significant as a prognostic factor in comparison to other factors such as ENE.

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晚期癌症喉部恶性软组织沉积物的前瞻性研究

本研究旨在评估晚期喉癌中恶性软组织沉积（MSTD）的发生率和预测因素。同时还研究了恶性软组织沉积物对治愈手术后两年内局部复发的预后价值。40 名 cT3/cT4 N0 喉鳞状细胞癌（SCC）患者参与了前瞻性研究。对软组织标本进行组织病理学检查，以确定是否存在 MSTD。4名患者出现了MSTD。六名患者有结节外扩展（ENE），其中四人出现了 MSTD。cTNM 分期、术前气管切开术、肿瘤分级和手术切缘与 MSTD 的发生率无关。我们报告中的MSTD发生率低于之前的文献报道。MSTD不影响局部复发，也不影响总体预后。与ENE等其他因素相比，MSTD对预后的影响较小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Otolaryngology and Head and Neck Surgery Medicine-Otorhinolaryngology

CiteScore

0.80

自引率

0.00%

发文量

226

审稿时长

6-12 weeks

期刊介绍： Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.